2004, Number s2
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Arch Cardiol Mex 2004; 74 (s2)
Rotors and fibrillation
Jalife J
Language: Spanish
References: 24
Page: 289-292
PDF size: 48.77 Kb.
ABSTRACT
Auricular or ventricular fibrillation is yet to be a vast field for discussion and research in basic and clinic electrophysiology. New hypothesis about non-linear wave dynamic propagation in excitable media, are focusing on the role rotors may play in the fibrillation mechanisms and two thinking currents derive from that. In one, inestability and translation of rotors is proposed whereas, the other one proposes a fracture and multiplication in the middle of myocardial structural anysopathy. Integration of non-linear wave dynamics propagation with recent findings of the molecular biology and ion channels biophysics is of such importance for the future development of antifibrilatory therapy.
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