2020, Number 2
Relationship between the consumption of psychoactive drugs and cognitive impairment in drug-dependent Ecuadorian patients
Language: Spanish
References: 26
Page: 543-558
PDF size: 310.61 Kb.
ABSTRACT
Introduction: the consumption of drugs and other psychoactive substances produces physical, social and mental damages, generating cognitive impairment, which causes difficulties in socialization and in memory operational components.Objective: to determine the correlation between cognitive impairment and the consumption of psychoactive substances in drug-dependent patients of the rehabilitation program, and its relationship with type of drug consumed and time of consumption, considering current age and educational level achieved.
Method: an observational, descriptive and cross-sectional study was conducted to determine the presence of cognitive impairment in 76 male drug-dependent patients between 18 and 66 years of age, admitted to the Unidad de Conductas Adictivas (UCA) of the Instituto de Neurociencias de Guayaquil (INC), Ecuador, between January and July, 2016. Folstein test (MMSE) was applied after 45 days of stay in the program and in abstinence from consumption, and deterioration was correlated with time of consumption and type of drugs.
Results: mild cognitive impairment was the most frequent, with a clear predominance of the age group between 18 and 24 years old which had 18 cases (64.3%), followed by the 25-29 age group with 14.3%.
Conclusions: approximately one in three cases showed some type of alteration with mild cognitive impairment and a strong association between the impairment and the time of consumption, but there was no evidence of its correlation with the type of drug consumed.
REFERENCES
Farré M, Abanades S. Aspectos cognitivos del consumo de cannabis. En: Atance JA. Aspectos psiquiátricos del consumo de cannabis. España: Universidad Complutense de Madrid; 2007. [citado 15/02/2019];[189p.]. Disponible en http://www.biblioteca.cij.gob.mx/Archivos/Materiales_de_consulta/Drogas_de_Abuso/Articulos/Diagnostico1.pdf#page=93
Samper Noa JA, Llibre Rodríguez JJ, Sánchez Catasús C, Pérez Ramos CL, Morales Jiménez E, Sosa Pérez S, et al. Miniexamen mental en sujetos con deterioro cognitivo leve. Rev Cubana Med Mil. 2012 [citado 20/01/2020]; 41(2): 125-132. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-65572012000200002
Toledo Fernández A, Villalobos-Gallegos L, Marín-NavarreteIs R. Es el Mini Examen del Estado Mental (MMSE) útil para el tamizaje de elegibilidad de participantes de investigación con un trastorno por uso de sustancias. RIIAD. 2016[citado 20/01/2020]; 2(1):39-44. Disponible en: https://doi.org/10.28931/riiad.2016.1.06 14. Crum RM, Anthony JC, Bassett SS, Folstein MF. Population-based norms for the Mini-Mental State Examination by age and educational level. JAMA. 1993[citado 20/01/2020]; 269(18):2386-2391. Disponible en: https://jamanetwork.com/journals/jama/article-abstract/405973
Fernández Serrano MJ, Pérez García M, Schmidt Río Valle J, Verdejo García A. Neuropsychological consequences of alcohol and drug abuse on different components of executive functions. J Psychopharmacol. 2010[citado 20/01/2020]; 24(9):1317-1332. Disponible en: https://journals.sagepub.com/doi/abs/10.1177/0269881109349841
Vonmoos M, Hulka LM, Preller, KH, Minder F, Baumgartner MR, Quednow BB. Cognitive impairment in cocaine users is drug-induced but partially reversible: evidence from a longitudinal study. Neuropsychopharmacology. 2014[citado 20/01/2020]; 39(9):2200-2210. Disponible en: https://www.nature.com/articles/npp201471 17. Potvin S, Stavro K, Rizkallah E, Pelletier J. Cocaine and cognition: a systematic quantitative review. J Addict Med. 2014[citado 20/01/2020]; 8(5):368-376. Disponible en: https://journals.lww.com/journaladdictionmedicine/Abstract/2014/09000/Cocaine_and_Cognition___A_Systematic_Quantitative.10.aspx
Lorea I, Fernández J, Tirapu J, Landa N, López-Goñi JJ. Rendimiento neuropsicológico en la adicción a la cocaína: una revisión crítica. Rev Neurol. 2010[citado 20/01/2020]; 51(7): 412-426. Disponible en: https://www.researchgate.net/profile/Inaki_Lorea/publication/297281148_Neuropsychological_performance_in_cocaine_addiction_a_critical_review/links/570b8a6808ae2eb942239280/Neuropsychological-performance-in-cocaine-addiction-a-critical-review.pdf
Coullaut Valera R, Arbaiza Diaz del Río I, de Arrúe Ruiloba R, Coullaut Valera J, Bajo Bretón R. Deterioro cognitivo asociado al consumo de diferentes sustancias psicoactivas. Actas Esp Psiquiatr. 2011[citado 20/01/2020];39(3):168-173.Disponible en: https://www.actaspsiquiatria.es/repositorio/13/71/ESP/13-71-ESP-168-173-776266.pdf
Arana JM, Gordillo F, Blanco C, Meilán J, Carro J, Pérez E, et al. Hay una relación entre el consumo de drogas y la memoria prospectiva. Ciencia Cognitiva. 2012[citado 20/01/2020];6:6-8. Disponible en: http://www.cienciacognitiva.org/files/2011-20.pdf 26. Arana JM, Blanco C, Meilán J, Pérez E, Carro J, Gordillo, F. The impact of poly drug use on several prospective memory measures in a sample of university student. Rev Latinoam Psicol. 2011[citado 20/01/2020]; 43(2): 229-240.Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-05342011000200003&lng=en&tlng=en
Verdejo García A, López Torrecillas F, Orozco Giménez C, Pérez García M. Impacto de los deterioros neuropsicológicos asociados al consumo de sustancias sobre la práctica clínica con drogodependientes. Adicciones. 2002[citado 20/01/2020];14(3):1-26. Disponible en: http://www.adicciones.es/index.php/adicciones/article/view/490/486