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2019, Number 4

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Rev Cubana Estomatol 2019; 56 (4)

Antibacterial effect of a toothpaste with xylitol on Streptococcus mutans in pregnant women's saliva

Escalante-Medina RP, Asmat-Abanto AS, Ruiz-Barrueto MA

Language: Spanish
References: 36
Page: 1-12
PDF size: 294.96 Kb.


ABSTRACT

Introduction: Some physiological changes occur in women during pregnancy which cause an increase in dental plaque and cariogenic microbiota. This situation, alongside a modification in the diet and inadequate oral hygiene, negatively affect the oral health of both the mother and the baby.
Objective: Determine the antibacterial effect of a toothpaste with xylitol on the count of Streptococcus mutans in pregnant women's saliva.
Methods: A double-blind clinical trial was conducted in José Olaya Health Center (Chiclayo, Peru) in January 2017. The sample population was 50 women in the second trimester of pregnancy who met the established inclusion criteria. Two groups were formed: 25 pregnant women used a toothpaste with 10% xylitol and the other 25 used a toothpaste without xylitol. A saliva sample was taken and processed microbiologically before the start of the study and 14 days after use of the two toothpastes. A count was performed of colony-forming units for Streptococcus mutans in saliva with highly significant reliability, using the intraclass correlation coefficient, and intra- and inter-rater calibration (1.000 and 0.999, respectively). Data analysis was based on the Mann-Whitney U Test, with a significance level of 5%.
Results: No significant difference was found between the pregnant women who used the toothpaste with xylitol and those who used the toothpaste without xylitol (p= 0.062).
Conclusions: The antibacterial effect of the commercial toothpaste with xylitol is similar to that of a toothpaste without xylitol in terms of the Streptococcus mutans count in pregnant women's saliva.


REFERENCES

  1. Pentapati KC, Acharya S, Bhat M, Rao SK, Singh S. Knowledge of dental decay and associated factors among pregnant women: A study from rural India. Oral Health Prev Dent. 2013;11(2):161-8.

  2. Vamos CA, Thompson EL, Avendano M, Daley EM, Quinonez RB, Boggess K. Oral health promotion interventions during pregnancy: a systematic review. Community Dent Oral Epidemiol. 2015;43:385-96.

  3. Kamate W, Vibhute N, Baad R. Estimation of DMFT, salivary Streptococcus mutans count, flow rate, Ph, and salivary total calcium content in pregnant and non-pregnant women: a prospective study. J Clin Diagn Res. 2017;11(4):147-51.

  4. Silva de Araujo C, Gonçalves C, Costa A, Abreu É, Fontoura M. Systemic alterations and their oral manifestations in pregnant women. J Obstet Gynaecol Res. 2017;43(1):16-22.

  5. Vergnes JN, Kaminski M, Lelong N, Musset AM, Sixou M, Nabet C. Frequency and risk indicators of tooth decay among pregnant women in France: a cross-sectional analysis. PLoS One. 2012;7(5):e33296.

  6. Kloetzel MK, Huebner CE, Milgrom P. Referrals for dental care during pregnancy. J Midwifery Womens Health. 2011;56(2):110-7.

  7. Raj R, Vaibhav V. Maternal Factors and Child Oral Health. Int J Health Sci Res. 2012;2(8).

  8. Weber K, Goebel BM, Drake DR, Kramer KW, Warren JJ, Reeve J, et al. Factors associated with mutans streptococci among young WIC-enrolled children. J Public Health Dent. 2012;72(4):269-78.

  9. Pitts NB, Zero DT, Marsh PD, Ekstrand K, Weintraub JA, Ramos-Gomez F, et al. Dental caries. Nat Rev Dis Primers. 2017;(3):1-16.

  10. Lin HK, Fang CE, Huang MS, Cheng HC, Huang TW, Chang HT, et al. Effect of maternal use of chewing gums containing xylitol on transmission of mutans streptococci in children: a meta-analysis of randomized controlled trials. Int J Paediatr Dent. 2016;26(1):35-44.

  11. Dhotre S, Suryawanshi N, Nagoba B, Selkar S. Rare and unusual isolates of viridans streptococci from the human oral cavity. Indian J Pathol Microbiol. 2016;59(1):47-9.

  12. Ojeda J, Oviedo E, Salas L. Streptococcus mutans y caries dental. CES Odontol. 2013;26(1):44-56.

  13. Biswas S, Biswas I. Complete genome sequence of Streptococcus mutans GS-5, a Serotype c Strain. J Bacteriol. 2012;194(17):4787-8.

  14. Alamoudi N, Hanno A, Almushayt A, Masoud M, El Derwi D. Early prevention of childhood caries with maternal xylitol consumption. Saudi Med J. 2014;35(6):592-7.

  15. Jung J, Cai J, Cho S, Song K, Jeon J. Influence of fluoride on the bacterial composition of a dual-species biofilm composed of Streptococcus mutans and Streptococcus oralis. Biofouling. 2016;32(9):1079-87.

  16. Chu J, Zhang T, He K. Cariogenicity features of Streptococcus mutans in presence of rubusoside. BMC Oral Health. 2016;16(1):54.

  17. Nilsson M, Rybtke M, Givskov M, Høiby N, Twetman S, Tolker-Nielsen T. The dlt genes play a role in antimicrobial tolerance of Streptococcus mutans biofilms. Int J Antimicrob Agents. 2016; 48(3):298-304.

  18. Milgrom P, Söderling EM, Nelson S, Chi DL, Nakai Y. Clinical evidence for polyol efficacy. Adv Dent Res. 2012;24(2):112-6.

  19. Sőderling E, Hirvonen A, Karjalainen S, Fontana M, Catt D, Seppa L. The effect of xylitol on the composition on the oral flora: A pilot study. Eur J Dent. 2011;5(1):24-31.

  20. Anand P, Anand U, Khandelwal V. The effect of xylitol on dental caries and oral flora. Clin Cosmet Investig Dent. 2014;(6):89-94.

  21. Harłukowicz K, Kaczmarek U. Effectiveness of xylitol in caries prevention. Dent Med Probl. 2015;52(4):479-84.

  22. Milgrom P, Ly K, Tut O, Mancl L, Roberts M, Briand K, et al. Xylitol pediatric topical oral syrup to prevent dental caries: a double-blind randomized clinical trial of efficacy. Arch Pediatr Adolesc Med. 2009;163(7):601-7.

  23. Padilla T, Castillo J, Catacora P. Efecto de la pasta dental con xylitol en el recuento de Streptococcus mutans en niños de 7 a 9 años. Estudio Piloto. Rev. Investig. Altoandin [Internet]. 2013 [citado 11 En 2017];15(1):75-86. Disponible en: http://huajsapata.unap.edu.pe/ria/index.php/ria/article/viewFile/18/16

  24. Ritter AV, Bader JD, Leo MC, Preisser JS, Shugars DA, Vollmer WM, et al. Tooth-surface-specific effects of xylitol: randomized trial results. J Dent Res [Internet]. 2013 [cited 2017 Jan 12];92(6):512-7. Available from: https://www.ncbi.nlm.nih.gov/pubmed/23589387

  25. Chi DL, Tut O, Milgrom P. Cluster-randomized xylitol toothpaste trial for early childhood caries prevention. J Dent Child (Chic) [Internet]. 2014 [cited 2017 Jan 12];81(1):27-32. Available from: https://www.ncbi.nlm.nih.gov/pubmed/24709430

  26. Evans A, Leishman SJ, Walsh LJ, Seow WK. Inhibitory effects of children's toothpastes on Streptococcus mutans, Streptococcus sanguinis and Lactobacillus acidophilus. Eur Arch Paediatr Dent [Internet]. 2015 [cited 2017 Jan 11];16(2):219-26 Available from: https://www.ncbi.nlm.nih.gov/pubmed/25403148

  27. Lee W, Spiekerman C, Heima M, Eggertsson H, Ferretti G, Milgrom P, et al. The effectiveness of xylitol in a school-based cluster-randomized clinical trial. Caries Res [Internet]. 2015 [cited 2017 Jan 11];49(1):41-9. Available from: https://www.ncbi.nlm.nih.gov/pubmed/25428785

  28. Riley P, Moore D, Ahmed F, Sharif MO, Worthington HV. Xylitol-containing products for preventing dental caries in children and adults. Cochrane Database Syst Rev [Internet]. 2015 [cited 2017 Jan 11];26(3):CD010743. Available from: https://www.ncbi.nlm.nih.gov/pubmed/25809586

  29. Duane B. Xylitol and caries prevention. Evid Based Dent [Internet]. 2015 [cited 2017 Jan 11];16(2):37-8. Available from: https://www.ncbi.nlm.nih.gov/pubmed/26114781

  30. Arat Maden E, Altun C, Açikel C. The Efficacy of Xylitol, Xylitol-Probiotic and Fluoride Dentifrices in Plaque Reduction and Gingival Inflammation in Children: A Randomised Controlled Clinical Trial. Oral Health Prev Dent [Internet]. 2017 [cited 2018 Aug 11];15(2):117-21. Available from: https://www.ncbi.nlm.nih.gov/pubmed/28322366

  31. Silva T, Faustino A, Moreira M, Rabelo A. The use of xylitol as a strategy for prevention of dental caries. Rev Odonto Ciênc. 2009;24(2):205-12.

  32. Bahria N, Tohidinik HR, Bahrif N, Iliatif HR, Moshki M, Darabie F. Educational intervention to improve oral health beliefs and behaviors during pregnancy: a randomized-controlled trial. J Egypt Public Health Assoc. 2015;90(2):41-5.

  33. Surdacka A, Stopa J. The effect of xylitol toothpaste on the oral cavity environment. J Prev Med. 2005;13(1-2):98-107.

  34. Nakai Y, Shinga C, Kaji M, Moriya K, Murakami K, Takimura M. Xylitol gum and maternal transmission of mutans Streptococci. J Dent Res. 2010;89(1):56-60.

  35. Jannesson L, Renvert S, Kjellsdotter P, Gaffar A, Nabi N, Birkhed D. Effect of a triclosan-containing toothpaste supplemented with 10% xylitol on mutans streptococci in saliva and dental plaque. A 6-month clinical study. Caries Res. 2002;36(1):36-9.

  36. Buzalaf MA, Hannas AR, Kato MT. Saliva and dental erosion. J Appl Oral Sci. 2012;20(5):493-502.




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