2020, Number 1
<< Back Next >>
Rev Cuba Endoc 2020; 31 (1)
Changes in the secondary sexual characteristics of the patient with gender dysphoria as a result of endocrine therapy in Cuba
Ovies CG, Domínguez AE, Gómez AM
Language: Spanish
References: 24
Page:
PDF size: 510.33 Kb.
ABSTRACT
Introduction: Transsexualism is an inconsistency between the sex with which someone was born and the sex he or she feels belong to; therefore, these subjects want to do changes in their physical appearance that are achieved through hormonal treatment.
Objective: To describe changes in the secondary sexual characteristics in patients with gender dysphoria in Cuba as a result of endocrine therapy.
Methods: A study was conducted to review the clinical records in 76 patients treated by gender dysphoria in the past 15 years. It was collected the information related to socio-demographic data and some physical changes as a result of the hormonal therapy. For data analysis were obtained frequency distributions of the qualitative variables, the mean and the standard deviation of the quantitative ones.
Results: The majority of patients correspond to male to female transsexuals (THM, by its acronym in Spanish). A year after, the majority of the patients already studied had a stage III or stage IV of breast development (45.3 % of these had stage III and 32.3 % had stage IV). A year after the start of the attention of the 58 patients, 41.4% had a pattern of triangular hair typical of the female sex which they feel identified with and after 2 years it increased to 80.5 %. After a year, there were evaluated 50 % of all cases and at that time only 5.1 % maintained intense facial hair, and more than half (56.8 %) had no facial hair. At the beginning, the mean of testicular volume was 17.4 mL, after 3 months it was 15.7 mL, after 6 months was 14.3 mL and 9.7 mL after a year.
Conclusions: Patients with gender dysphoria in most cases achieve changes in the secondary sexual characteristics in accordance with the sex which they feel identified with.
REFERENCES
Wilson P, Sharp C, Carr S. The prevalence of gender dysphoria in Scotland: a primary care study. Br J Gen Pract. 1999;49:991-2.
Bakker A, Van Kesteren PJ, Gooren LG, Bezemer PD. The prevalence of transsexualism in The Netherlands. Acta Psychiatr Scand. 1993;87:237-8.
Esteva I, Gonzalo M, Yahyaoui R, Domínguez M, Bergero T. Giraldo F. Epidemiología de la transexualidad en Andalucía, atención especial al grupo de adolescentes. Cuad Med Psicosom. 2006;78:65-70.
Gómez E, Trilla A, Godás T, Halperin I, Puig M, Vidal A. Estimación de la prevalencia, incidencia y razón de sexos del transexualismo en Cataluña según la demanda asistencial. Actas Esp Psiquiatr. 2006;34:295-302.
Fernández M, García-Vega E. Seguimiento, evolución y dificultades del diagnóstico de transexualismo. Rev. Asoc. Esp Neuropsiq. 2012;32:103-119.
Moreno O, Esteva de A. Guía de práctica clínica para la valoración y tratamiento de la transexualidad. Grupo de identidad y diferenciación sexual de la SEEN. Rev Nutr. 2012;59:367-82.
Fernández M, García Vega E. Variables clínicas en el trastorno de identidad de género. Psicothema. 2012;4:555-80.
Garrels L, Kockott G, Michael N, Preuss W, Renter K, Schmidt G, et al. Sex ratio of transsexuals in Germany: the development over three decades. Acta Psychiatrica Scandinavica. 2000;102:445-448.
Landén M, Walinder J, Lunströn B. Prevalence, incidence and sex ratio of transsexualism. Acta Psychiatrica Scandinavica. 1996;93:221-3.
Olsson S, Moller A. On the incidence and sex ratio of transsexualism in Sweden, 1972-2002. Arch Sex Behav. 2003;32:381-6.
Weitze C, Osburg S. Transsexualism in Germany: empirical data on epidemiology and application of the Germans transsexualism act during its first years. Arch Sex Behav. 1996;25:409-25.
Hurtado F, Gómez M, Donat F. Transexualismo y Salud Mental. Rev Psicopatologìa y Psicol Clin. 2007;12:43-57.
Anuario Estadístico de Cuba. La Habana: ONE; 2012.
Martínez A. La construcción social del cuerpo en las sociedades contemporáneas. Papers. 2004;73:127-52.
Morales J. La mujer en la escultura: Cuerpo y símbolo. Arbor. CLXVIII 2001; 663:379- 88.
Meegan J, Lloyd G. Advances in the Science of Estrogen Receptor Modulation. Curr Med Chem. 2003;10:181-210.
Coromoto Y. Receptores de estrógenos, estructura, mecanismo de acción y su relación con el desarrollo de embriones de mamíferos. Boletín Med Postg. 2009;25:1-10.
Alonso C. Tratamiento Hormonal Cruzado. Hormonización de personas trans. Boletín Ministerio Salud Pública MSP. Uruguay; 2014.
Hadj- Moussa M, Ohl D, Kuzon W. Evaluation and Treatment of gender dysphoria to prepare for gender confirmation surgery. Sex Med Rev. 2018;43:1-11.
De Block CJ, Klaver M, Wiepjers C, Marije N, Corine A, Daphne A, et al. Breast develoment in transwomen after 1 year of cross-sex hormone therapy: Results of a prospective multicenter study. J Clin Endocrinol Metab. 2018;103:532-8.
Protocolo de Atención Sanitaria a Personas Transexuales. Consejería de Sanidad, Servicio Canario de Salud, Dirección General de Programas Asistenciales. España: Gobierno de Canarias; 2009.
Gooren L. The endocrinology of sexual behaviour and gender identity, at Endocrinology: Adult and Pediatric. Chapter 124. 2016;2163-76.
Giltay E, Gooren, L. Effects of sex steroid deprivation/administration on hair growth and skin sebum production in trans- sexual males and females. J Clin Endocrinol Metabol. 2000;85:2913–2921.
Fisher M. Endocrine Treatment of Transexual Male-to-Female Persons, at Managment of Gender Dysphoria: A multidisciplinary approach. Endocrinology. Chapter 10; 2015.