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2020, Number 2

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Rev Educ Bioquimica 2020; 39 (2)

Producción y función de especies reactivas de oxígeno en plaquetas

Hernández-García S, Meneses MFC, Calderón-Salinas José-Víctor

Language: Spanish
References: 59
Page: 52-60
PDF size: 307.50 Kb.


ABSTRACT

The platelets are anucleated blood cells, participate in vascular hemostasis, inflammation and the defense against pathogens; have complex signaling intracellular cascades that can be activated by physiological molecules from the membrane localized receptors. Intracellular signaling can also be regulated by reactive oxygen species production. This review summarizes information about the intraplaquetary reactive oxygen species production, its role in platelet activation and in pro-thrombotic states and the antioxidant enzymes that modulate their bioavailability.


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