2019, Number 4
Severe coronary artery disease and ST segment shift in lead aVR in non ST segment elevation acute Coronary Syndrome
Language: Spanish
References: 23
Page:
PDF size: 829.86 Kb.
ABSTRACT
Introduction: ST-segment shift in lead aVR is associated with increased coronary aterosclerosis. However, there is insufficient data about it relationship with coronary complexity.Objetive: To determinate the contribution of ST segment shif in lead aVR in diagnosis of complex coronary heart disease comfirm after by angiography.
Method: Analytic, cross sectional study in patients with non ST segment elevation acute coronary syndrome hospitalized in Coronary Care Unit at Hospital Hermanos Ameijeiras and Hospital Enrique Cabrera from may 2011 to may 2017.
Results: Male patients (52,9 %) with a mean age 66,0 ± 8,0 and more than two comorbidities (92,2 %) were predominant. Left main disease (99,3 %) and multivessels disease (43 %) with stenosis ≥ 70 % (94,4 %) were more frequent in ST segment shitf lead aVR> 1 mm. Also in this group B2 and C lesion type were predominant (73,2 and 87,5 %). A sensibility of 84,5 % and specificity of 69,8 % was obtained for the diagnosis of complex coronary heart disease with an area under the curve of 0,893 (IC 95 %= 0,879-0,907; p=0,00). The positive predictive value was 81,6 % and the negative predictive value was 74,3 %.
Conclusion: ST segment shift in lead aVR ≥ 1,0 mm was an important predictor of complex coronary heart disease in non ST segment elevation acute coronary syndrome.
REFERENCES
Liang D, Zhang J, Lin L, Zong W. The differenceon features of fragmented QRS complex and influences on mortality in patientes with acute coronary syndrome Acta Cardiol Sin [Internet]. 2017 Nov [cited 2019 Abr 11]; 33(6) :588-95. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694921/ .
Roffi M, Patrono C, Collet JP, Mueller C, ValgimigliM, Andreotti F, et al. Guía ESC 2015 sobre el tratamiento de los síndromes coronarios agudos en pacientes sin elevación persistente del segmento ST. Rev Esp Cardiol [Internet].2015 Dic [citado 19 Nov 2018];68(12):1-64. Disponible en: http://www.revespcardiol.org/es/guia-esc-2015-sobre-el/articulo/90445376/
Barrabés JA, Figueras J, Moure C, Cortadellas J,Soler-Soler J.Prognostic value of lead aVR in patients with a first non–ST- Segment elevation acute myocardial infarction. Circulation [Internet]. 2003 Aug [cited 2018 Sep 26]; 108:814–9. Available from: https://www.ahajournals.org/doi/full/10.1161/01.CIR.0000084553.92734.83?url_ver=Z39.882003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed.
Yamaji H, Iwasaki K, Kusachi S, Murakami T,Hirami R, Hamamoto H, et al. Prediction of acute left main coronary artery obstruction by 12-lead electrocardiography: ST segment elevation in lead aVR with less ST segment elevation in lead V1. J AmColl Cardiol [Internet]. 2001 Nov [cited 2019 Mar 21];38(5):1348–54. Available from: https://www.sciencedirect.com/science/article/pii/S0735109701015637?via%3Dihub.
Misumida N, Kobayashi A, Fox JT, Hanon S,Schweitzer P, Kanei Y. Predictive value of ST segment elevation in lead aVR for Left Main and/or Three vessel disease in non-ST-segment elevation myocardial infarction. Ann Noninvasive Electrocardiol [Internet]. 2016 Jan [cited 2018 Nov 12];21(1):91-7. Available from: https://www.ncbi.nlm.nih.gov/pubmed/25884447
Taglieri N, Marzocchi A, Saia F, Marrozzini C,Palmerini T, Ortolani P, et al. Short and long-term prognostic significance of ST-segment elevation in lead aVR in patients with non ST segment elevation acute coronary syndrome. Am J Cardiol. [Internet].2011 Jul [cited 2018 Oct 19];108(1);21-8. Available from: https://www.ajconline.org/article/S0002-9149(11)01139-8/fulltext
Ali L, Asgahr N, Hussain A, Shah M. ST segmentelevation in lead aVR: Clinical significance in acute coronary syndrome. Ann Pak Inst Med Sci [Internet] 2016 [cited 2019 Mar 21]; 12(4):203-8. Available from: https://apims.net/apims_old/Volumes/Vol12-4/ST%20SEGMENT%20ELEVATION%20IN%20LEAD%20aVR%20CLINICAL%20SIGNIFICANCE%20IN%20ACUTE%20CORONARY%20SYNDROME.pdf.
Hussien A, Battah A, Ashraf M, El-Deen ZT.Electrocardiography as a predictorof left main or three-vessels disease in patients with non ST segment elevation acute coronary syndrome. Egypt Heart J [Internet].2011 Jun [cited 2019 Mar 23];63(2):103-Available from: https://www.researchgate.net/publication/257498320_Electrocardiography_as_a_predictor_of_left_main_or_three vessel_disease_in_patients_with_non ST segment elevation acute coronary_syndrome
Kosuge M, Kimura K, Ishikawa T, Ebina T, Hibi K,Tsukahara K, et al. Combined prognostic utility of ST segment in lead aVR and troponin T on admission in non-ST-segment elevation acute coronary syndromes. Am J Cardiol [Internet] 2006 Feb [cited 2018 Sep 26]; 97(3):334 –9. Available from: https://www.sciencedirect.com/science/article/pii/S0002914905018199?via%3Dihub.
García Hernández RA, Prohías Martínez JA, SerielRivero L, Leyva Quert AY, Sánchez Cruz R, Tirado Céspedes Y. Valor pronóstico de la elevación del segmento ST en la derivación aVR en el síndrome coronario agudo sin elevación del segmento ST. Rev cuban cardiol [Internet]. 2015 Nov [citado 11 Oct 2018];21 (4):[aprox. 7p.]. Disponible en: http://www.revcardiologia.sld.cu/index.php/revcardiologia/article/view/618
García Hernández RA, Seriel Rivero L. Valorpronóstico del segmento ST en la derivación aVR en el síndrome coronario agudo sin elevación del segmento ST. Rev Arg Cardiol [Internet]. 2018 Jul-Sep [citado 12 Nov 2018]; 47(3):120-4. Disponible en:www.fac.org.ar/2/revista/18v47n3/original/01/hernandez.pdf
Loáisiga Ruiz RJ. Evolución clínica del síndromecoronario agudo en pacientes ingresados en el hospital regional San Juan de Dios de Esteli en el período enero del 2014 a diciembre del 2014. [Tesis]. Managua, Nicaragua: Universidad Nacional Autónoma de Nicaragua; 2016[citado 22 Nov 2016]. Disponible en: http://repositorio.unan.edu.ni/1588/
Yamaji H, Iwasaki K, Kusachi S, Murakami T,Hirami R, Hamamoto H, et al. Prediction of acute left main coronary artery obstruction by 12-lead electrocardiography: ST segment elevation in lead aVR with less ST segment elevation in lead V1. J AmColl Cardiol [Internet]. 2001 Nov [cited 2019 Mar 21];38(5):1348–54. Available from: https://www.sciencedirect.com/science/article/pii/S0735109701015637?via%3Dihub.
Yan AT, Yan RT, Kennelly BM, Anderson Jr FA,Budaj A, López-Sendón J, et al. Relationship of ST elevation in lead AVR with angiographic findings and outcome in non ST elevation acute coronary syndrome. Am Heart J [Internet].2007 Jul[cited 2019 Mar 21]; 154(1):71-8. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0002-8703(07)00261-X.
Kosuge M, Toshiaki E, Hibi K, Morita S, Endo M,Maejima N, et al. An early and simple predictor of severe left main/or three vessel disease in patients with non ST segment elevation acute coronary syndrome. Am J Cardiol [Internet] 2011 Feb [cited 2019 Apr 11];107(4):495-500. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0002-9149(10)02088-6.
Gachchhadar PK, Mahmood M, Adhikary DK,Chowdhury T. Significance of ST segment elevation in lead aVR in non-ST elevation acute coronary syndrome. Univ Hear J [Internet] 2018 Jul [cited 2019 Mar 30];14(2):71-6. Available from: https://www.researchgate.net/publication/331161430_Significance_of_ST_SegmentElevation_in_Lead_aVR_in_Patients_with_Non ST elevation acute coronary syndrome.
Oliver Rengifo PG, Ríos Oliva C. Característicasclínicas, morbilidad y mortalidad de los pacientes con síndrome coronario agudo y elevación del segmento ST en la derivada aVR. Rev Soc Perú Med Interna [Internet] 2013 [citado 15 Abr 2019];26(4):177-83. Disponible en: http://medicinainterna.net.pe/pdf/2013/vol26num4/trabajo%20orig5.pdf.
Kosuge M, Ebina T, Hibi K, Endo M, Komura N,Hashiba K, et al. ST-Segment elevation resolution in lead aVR- A strong predictor of Adverse Outcomes in patiens with Non ST-Segment Elevation Acute Coronary Syndrome. Circ J [Internet] 2008 Jul [cited 2019 Mar 22]; 72: 1047-53. Available from: https://www.jstage.jst.go.jp/article/circj/72/7/72_7_1047/_article.