Islas GD, Alderete BJ, Quiróz SCV, Perera CRN

Language: Spanish
References: 25
Page: 233-238
PDF size: 314.90 Kb.

ABSTRACT

Hypothalamic hamartomas are malformations originated at the tuber cinereum and lower hypothalamus. It is a rare condition, with an estimated prevalence of 1 to 2 cases per 100,000 inhabitants. The classic clinical presentation is a triad that includes gelastic crises, developmental delay, and central precocious puberty. However, it has been seen that hypothalamic hamartomas have a broad spectrum in their clinical and electroencephalographic presentation, so their diagnosis can be quite a challenge because some symptoms may not appear, especially in cases that have a benign course. We present the case of a patient with gelastic seizures that began in early childhood originated from a hypothalamic hamartoma, with absence of cognitive impairment and endocrinological alterations, for which the diagnosis was made until adolescence due to the little impact that the seizures had on her life quality. She was surgically treated with laser ablation, currently seizure free.

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