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Revista de la Asociación Médica del Centro Médico ABC

2020, Number 3

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An Med Asoc Med Hosp ABC 2020; 65 (3)

Electroencephalographic findings in patients with confirmed SARS-CoV-2/COVID-19 diagnosis

Shkurovich-Bialik P, Evangelio-Miranda JD, Maldonado-Torres GÁ

Language: Spanish
References: 20
Page: 194-200
PDF size: 303.95 Kb.


ABSTRACT

Introduction: Coronavirus disease 2019 (COVID-19) has recently emerged as a pandemic characterized by an acute respiratory syndrome. Neurological involvement by the virus have recently been described. To date, there is little evidence of the electroencephalographic (EEG) changes associated with the disease. Objective: To describe the findings of video-electroencephalography in patients with COVID-19 performed at the ABC Medical Center. Material and methods: A retrospective analysis of electroencephalography of patients diagnosed with COVID-19 was performed. Information regarding age, gender, study indication, disease severity, metabolic status, lung-CT scan severity, neuroimaging findings, medications at the time of the study, patient evolution, and electroencephalographic findings was analyzed. Results: 14 electroencephalography were identified in 11 patients. All patients had SARS-CoV-2/COVID-19 positive PCR test. The indications were: 6 for suspicion of epileptic activity, 7 for alteration in alertness and 1 for agitation. The average age was 56 (22-77), 9 men. By severity scale 1 (9.09%) had mild illness, 1 (9.09%) moderate degree, 1 (9.09%) severe and 8 (72.72%) critical degree. electroencephalography showed background slowing, loss of gradients and poor reactivity in 12 (85.71%) studies, all of them with severe to critically ill disease. Triphasic waves were found in 3 (21.42%), generalized slowing in 3 (21.42%), generalized periodic patterns in 2 (14.28%), 1 (7.14%) burst-suppression pattern, and 1 (7.14%) with generalized interictal epileptiform activity in a patient with history of epilepsy. Conclusion: The electroencephalography results correlate between the patient’s clinical status with certain findings in the electroencephalography records. Larger samples and longer patient follow-up are required to confirm these findings.


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