2020, Number 2
Serological markers of infection and exposure to hepatitis B in voluntary blood participants
Language: Spanish
References: 9
Page: 76-80
PDF size: 249.59 Kb.
ABSTRACT
Introduction: Knowing the behavior of serological markers of infection and exposure to hepatitis B virus in blood donors is a way of appreciating the results of the National Immunization Program and indirectly weighing the safety of blood for transfusions. Objective: Describe serological markets of the hepatitis B in blood donors. Material and methods: A descriptive study was conducted to determine the prevalence of hepatitis B virus (HBV) markers (HBsAg and total anti-HBc) in 220 blood donors from the province of Cienfuegos selected in a simple random way during the months of January to May 2019. Results: There was no positive case for HBsAg. The prevalence of anti-HBc was 9.54% (21/220), with a significant increase with age. No cases of HBsAg and anti-HBc positive were found in individuals born after the introduction of HBV vaccination in the country. Conclusions: In the donors studied, the prevalence of serological markers of hepatitis B is low and nil in those born after vaccination against HBV. Therefore, the risk of HBV transmission due to the use of transfusions or blood products must be reduced, because the donor population will continue to be replaced by immunized individuals. All this contributes to the elimination of hepatitis B as a health problem in Cuba.REFERENCES
López Ambrón L, Egües Torres LI, Pérez Carreras A, Galindo Santana BM, Galindo Sardiña MA, Resik Aguirre S et al. Experiencia cubana en inmunización, 1962-2016. Rev Panam Salud Publica [Internet]. 2018 [citado 30 dic 2019]; 42: [aprox. 16 p.]. Disponible en: http://iris.paho.org/xmlui/bitstream/handle/123456789/34905/v42e342018.pdf?sequence=1&isAllowed=y
Pérez Ulloa LE. Programa Nacional de Sangre. Comité hospitalario de Medicina Transfusional. En: Ballester Santovenia JM, Alfonso Valdés ME, Bencomo Hernández AA, Macías Abraham C. ABC en medicina transfusional. Guías clínicas. 2a ed. La Habana: Instituto de Hematología e Inmunología; 2016. pp. 179-182.