2020, Number 08
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Revista Médica Sinergia 2020; 5 (08)
Acute osteomyelitis: classification, pathophysiology, and diagnosis
Brenes MM, Gómez SN, Orozco MD
Language: Spanish
References: 25
Page: 1-19
PDF size: 201.16 Kb.
ABSTRACT
Acute osteomyelitis is an infectious and inflammatory process of the bone
that can involve from the medulla to the cortex. It is characterized by a
period of evolution of no more than two weeks from the onset of symptoms
until diagnosis. It is frequently classified according to its etiology, anatomy,
and comorbidities. Acute osteomyelitis can originate from an infectious
focus adjacent to the bone, by hematogenous route or direct inoculation. It
is usually unifocal, frequently affecting the metaphyses of long bones,
especially the femur, tibia, and humerus. The etiologic agent identified in
most cases regardless of the age group is Staphylococcus aureus. The
clinical presentation depends on the age group and the etiology. Diagnosis
is based on medical history, laboratory tests, and imaging techniques.
REFERENCES
Freire, Luis Francisco Llerena, et al. Osteomielitis: abordaje diagnóstico terapéutico. Archivos Venezolanos de Farmacologia y Terapéutica 38.1 (2019): 53-62
Rojas Solano María Jesús, Badilla García Jenny. Osteomielitis Aguda: Características Clínicas, Radiológicas y de Laboratorio. Medicina Legal de Costa Rica. 2018. 35 (2), 54-61. Disponible en: http://www.scielo.sa.cr/scielo.php?script=sci_arttext&pid=S1409-00152018000200054&lng=en&tlng=es.
Álvarez López, Alejandro, Sergio Ricardo Soto-Carrasco, Yenima de la Caridad García Lorenzo. Osteomielitis: enfoque actual. Revista Archivo Médico de Camagüey 22.1 (2018): 94-104.
Chiappini E, Mastrangelo G, Lazzeri S. A Case of Acute Osteomyelitis: An Update on Diagnosis and Treatment. International Journal of Environmental Research and Public Health. 2016 05 27;13(6):539. https://doi.org/10.3390/ijerph13060539
Kavanagh N, Ryan EJ, Widaa A, Sexton G, Fennell J, O'Rourke S, Cahill KC, Kearney CJ, O'Brien FJ, Kerrigan SW. Staphylococcal osteomyelitis: disease progression, treatment challenges, and future directions. Clin Microbiol.2018. Rev 31:e00084-17. https://doi.org/10.1128/CMR.00084-17.
Ugalde Ovares, Carlos Eduardo, Morales Castro, Diana. Osteomielitis. Medicina Legal de Costa Rica. 2014 31 (1), 94-102. Disponible en : http://www.scielo.sa.cr/scielo.phpscript=sci_arttext&pid=S1409- 00152014000100010&lng=en&tlng=es
E. Múñez Rubioa, I. Pintos Pascualb, A. Ramos Martínez. Osteomielitis. Medicine. 2018; 12(55):3262-71. Doi: 10.1016/j.med.2018.04.013. https://doi.org/10.1016/j.med.2018.04.013
Saavedra-Lozano J, Calvo C, Huguet Carol R, Rodrigo C, Núñez E, Pérez C, Merino R, Rojo P, Obando I, Downey F, Colino E, García J, Cilleruelo M, Torner F, García L. Documento de Consenso SEIP-SERPESEOP sobre etiopatogenia y diagnóstico de la osteomielitis aguda y artritis séptica no complicadas. Anales de Pediatría. 2015 09;83(3):216.e1- 216.e10. https://doi.org/10.1016/j.anpedi.2014.08.006
Kremers HM, Nwojo ME, Ransom JE, Wood-Wentz CM, Melton LJ, Huddleston. Trends in the Epidemiology of Osteomyelitis.J Bone Joint Surg Am. 2015;97(10):837-45. https://doi.org/10.2106/JBJS.N.01350
Yagupsky P. Microbiological Diagnosis of Skeletal System Infections in Children. Current Pediatric Reviews. 2019 Dec 09;15(3):154-163. https://doi.org/10.2174/1573396315666190408114653
Areg Grigorian, Sebastian Schubl, John Scolaro, Nathan Jasperse, Viktor Gabriel, Allison Hu, Gino Petrosian, Victor Joe, Jeffry Nahmias. No increased risk of acute osteomyelitis associated with closed or open long bone shaft fracture. Journal of Clinical Orthopaedics and Trauma 10 (2019) S133eS138. https://doi.org/10.1016/j.jcot.2019.04.003
Robinette ED, Brower L, Schaffzin JK, Whitlock P, Shah SS, Connelly B, . Use of a Clinical Care Algorithm to Improve Care for Children With Hematogenous Osteomyelitis. Pediatrics. 2018 Dec 19;143(1):e20180387. https://doi.org/10.1542/peds.2018-0387
Nimmy Thakolkaran, Avinash K. Shetty. Acute Hematogenous Osteomyelitis in Children. Ochsner Journal 19:116-122, 2019. https://doi.org/10.31486/toj.18.0138
Sergio Alejandro Gómez Ochoa, Cristian David Sosa Vesga. Una visión actualizada sobre factores de riesgo y complicaciones de la osteomielitis pediátrica. Revista Cubana de Pediatría. 2016;88(4)
Nicole Le Saux. Diagnosis and management of acute osteoarticular infections in children. Paediatrics & Child Health, 2018, 336–343. https://doi.org/10.1093/pch/pxy049
Carlos Eduardo Ugalde Ovares, Diana Morales Castro. Osteomielitis. Medicina Legal de Costa Rica. 2014 Vol 31,1. ISSN 1409-0015.
Andrew J. Hotchen, Martin A. McNally, Parham Sendi. The Classification of Long Bone Osteomyelitis: A Systemic Review of the Literature. Journal of Bone and Joint Infection. 2017; 2(4): 167-174. https://doi.org/10.7150/jbji.21050
Steven K. Schmitt. Osteomyelitis. Infect Dis Clin N Am 31 (2017) 325–338. https://doi.org/10.1016/j.idc.2017.01.010
Shawn S. Funk, Lawson A.B. Copley. Acute Hematogenous Osteomyelitis in Children: Pathogenesis, Diagnosis, and Treatment. Orthop Clin N Am 48 (2017) 199–208 https://doi.org/10.1016/j.ocl.2016.12.007
María Jesús Rojas Solano, Pablo Vargas Rodríguez. Osteomielitis aguda: características clínicas, radiológicas y de laboratorio. Revista Médica de Costa Rice y Centro América. LXXII. 2015 (615) 347 – 354. Disponible en : https://www.binasss.sa.cr/revistas/rmcc/615/art22.pdf
Enrique Espinosa Hernández. Características clínicas según grupos de edad, agente causal, localización y hallazgos radiológicos de la osteomielitis hematógena en edad pediátrica. Revista Médica de Costa Rica y Centro América LXXIII. 2016 (619). 303-317. Disponible en: https://www.medigraphic.com/pdfs/revmedcoscen/rmc-2016/rmc162s.pdf.
Thakolkaran N, Shetty AK. Acute Hematogenous Osteomyelitis in Children. Ochsner Journal. 2019;19(2):116-122. https://doi.org/10.31486/toj.18.0138
Lee YJ, Sadigh S, Mankad K, Kapse N, Rajeswaran G. The imaging of osteomyelitis. Quantitative Imaging in Medicine and Surgery. 2016 04;6(2):184-198. https://doi.org/10.21037/qims.2016.04.01
Alexios D. Iliadis. Manoj Ramachandran. Pediatric bone and joint infection. EFORT Open Rev 2017; 1:7- 12. https://doi.org/10.1302/2058-5241.2.160027
Quick RD, Williams J, Fernandez M, Gottschalk H, Cosgrove P, Kahlden K, Merkel K, Thoreson L, Boswell P, Hauger SB. Improved Diagnosis and Treatment of Bone and Joint Infections Using an Evidence-based Treatment Guideline. Journal of Pediatric Orthopaedics. 2018 07;38(6):e354- e359. https://doi.org/10.1097/bpo.0000000000001187