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Colegio de Medicina Interna de México.

2020, Number 4

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Med Int Mex 2020; 36 (4)

Severe pneumonia due to COVID-19 cured with conscious proning and tocilizumab. A report of a case and review of the pharmacological therapeutic evidence

Del Carpio-Orantes L, González-Segovia O, Mojica-Ríos F, Suárez-Mandujano MP, Martínez-Rojas M, Cortés-Román JS, Jiménez-Flores OR, Pascual-Epigmenio S, Ramírez-Rojas R, Ataxca-González MA

Language: Spanish
References: 37
Page: 585-595
PDF size: 380.54 Kb.


ABSTRACT

Background: At the end of December 2019 it was described the first outbreak of atypical pneumonias in Wuhan, China, with the following detection of the agent of the genus coronavirus, today denominated SARS-CoV-2 and its disease COVID-19.
Clinic case: A 41-year-old male patient affected by COVID-19 in the form of severe pneumonia (CORADS-6), who had no response to conventional drugs that only added comorbidity (QT prolongation), deserving non-invasive ventilatory strategy in the prone and conscious mode, combined with the administration of tocilizumab, presenting adequate clinical, blood gas, and tomographic evolution, currently without pulmonary sequelae.
Conclusions: Many controlled clinical studies are still lacking in order to demonstrate the concrete utility of a specific drug and the current evidence leads to abandoning initially proposed schemes; however, some drugs may still have some utility in mild to moderate cases.


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