2020, Number 1
Characterization of the complications of patients diagnosed with cholera in the Pediatric Hospital of Centro Habana, 2013-2017
Language: Spanish
References: 19
Page: 1-14
PDF size: 437.02 Kb.
ABSTRACT
Introduction: The seventh cholera pandemic arrived to the Americas in 1991. In Cuba for more than 130 years there were no case reports.Objectives: To identify and characterize the complications by cholera and its relation with clinical characteristics and treatment.
Methods: A descriptive and prospective study was conducted from 2013 to 2017 to the patients who had been confirmed with V. cholerae as exclusive cause of acute diarrheal disease. The qualitative variables were described statistically using absolute and relative frequencies, and for the quantitative variables were used the average, medium, and standard deviation and the interquartile range as dispersion measures.
Results: 36.5% of the patients presented complications where dehydration was the most frequent. The value of the median time between the onset of symptoms and attention in the center was lower in patients with complications in comparison with the observed in non-complicated patients, but the difference was not significant (24.0 h [RI: 24,0-72,0 h] vs. 48,0 h [RI: 24,0-72,0 h], p= 0.355).
Conclusions: Most of the patients did not present complications and the most frequent is the slight dehydration.
REFERENCES
Zelada-Valdés A, Ledón-Pérez Talena Y, Fando-Calzada RA. El cólera: una enfermedad infecciosa reemergente. El candidato vacunal cv 638, una herramienta para su prevención. Revista CENIC. Ciencias Biológicas. 2015 [acceso 27/11/2019];46(2):131-43. Disponible en: https://www.redalyc.org/articulo.oa?id=181237108003
Salinas PJ. Cólera: Una revisión actualizada. Parte 3. Complicaciones del cólera. Tratamiento. Genética del cólera. Mecanismos de control de la epidemia. Mérida. Venezuela. Rev Facultad de Medicina. Universidad de Los Andes. 2018. Disponible en: http://www.sld.cu/galerias/pdf/sitios/ santiagodecuba/ colera-_3.pdf.
Nadri J, Sauvageot D, Njanpop-Lafourcade BM, Baltazar CS, BanlaKere A, Bwire G, Coulibaly D, et al. Sensitivity, Specificity, and Public-Health Utility of Clinical Case Definitions Based on the Signs and Symptoms of Cholera in Africa. Am J TropMed Hyg. 2018;98(4):1021-30. doi: 10.4269/ajtmh.16-0523. Epub 2018.
Silva H, Lopez F, Alvarado A, Valdez G. Insuficiencia renal aguda durante una epidemia de cólera, experiencia del Servicio de Nefrología del Hospital Dos de Mayo. Rev Med Herediana. 1991 [acceso 14/03/2019];(2):2. Disponible en: http://www.upch.edu.pe/vrinve/ dugic/revistas/index.php/RMH/article/view/335
Miyahira J, Acosta R, Zurita S, Torres C. Insuficiencia renal aguda en el Hospital Nacional Cayetano. Heredia, durante la epidemia del cólera. Rev Méd Herediana 2013 [acceso 22/11/2019];(2) Disponible en: https://www.researchgate.net/publication /299524476 16. Piarroux R, Rebaudet S. Cholera. Rev Prat. [acceso 22/11/2019] 2017;67(10):1117-1121 Disponible: https://www.ncbi.nlm.nih.gov/pubmed/30512613 PMID:30512613
Speelman P, Butler T, Kabir I, Ali A, Banwell J. Colonic dysfunction during cholera infection. Gastroenterology. 1986 [acceso 2/11/2019];91(5):1164-70. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/3758608 20. Fanous M, King KC. Cholera. In: StatPearls Treasure Island (FL): StatPearls Publishing; 2019.