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2019, Number 4

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Rev Cubana Med Gen Integr 2019; 35 (4)

Family aggregation for cervical cancer

Pérez PA, Gonzáles MIZ, Rodríguez LRL, Terrero QL

Language: Spanish
References: 16
Page: 1-6
PDF size: 136.58 Kb.


ABSTRACT

Introduction: Cervical cancer is a malignant neoplasm originating in the cervix uteri, mainly in the transformation area where squamous and glandular cells converge.
Objective: Determine the existence of family aggregation for cervical cancer.
Methods: An analytical cross-sectional case-control family aggregation study was conducted of patients attending the Gynecologic Oncology Service at Vladimir Ilich Lenin General University Hospital from September 2017 to February 2018. The sample was 60 women with a histological diagnosis of cervical cancer (cases) and 60 women without an oncological diagnosis (controls). Both groups were recruited from the health areas in the municipality of Holguín and paired by age.
Results: In the case group there was a greater frequency of family antecedents of cervical cancer, which was higher for first-degree relatives (31 relatives, 41.3%). A history of vaginal infection was the most common risk factor with 36.7% in the case group and 37.1% in the control group. It was determined that the risk for cervical cancer is approximately fourfold greater among individuals with a positive first-degree family history, whereas women with antecedents of vaginal infection were at 4.8 times greater risk for cervical cancer.
Conclusions: The study determined the existence of family aggregation for cervical cancer, with a greater risk for the disease among women with a positive family history and antecedents of vaginal infection.


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