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Medicina & Laboratorio

2014, Number 11-12

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Medicina & Laboratorio 2014; 20 (11-12)

Mammogram’s effectiveness as a screening test to reduce breast cancer mortality: A systematic review

Bonilla-Sepúlveda ÓA

Language: Spanish
References: 63
Page: 555-574
PDF size: 339.30 Kb.


ABSTRACT

Introduction: Mammography is a widely used diagnostic test for early detection of breast cancer in their subclinical stage. Moreover, it is safe and accepted by most patients, and allows timely establishment of medical or surgical treatment. Different studies have confirmed the effectiveness in preventing death from breast cancer; however, the current magnitude is less than the previously reported. Objective: To describe the main information available on reducing mortality from breast cancer due to the use of mammography as a screening test. Material and methods: A systematic review was conducted to search publications included in the Medline-PubMed, Cochrane and SciELO, using the terms “breast cancer screening”, “mammographic screening”, “assessing the impact of screening mammography”, “assessment of the effectiveness of mammography screening”, “effect of screening mammography on breast-cancer”, “breast cancer screening update“, among others. The original articles, clinical trials, reviews, systematic reviews and meta-analysis, written in English, published between 1986 and 2014, which used the screening mammography, were selected. Results: From systematic search, 63 publications transcendent to determine the effectiveness of screening mammography were included to the writing of this manuscript. Conclusions: Mammography remains the mainstay for screening of breast cancer, despite the wide variation between studies regarding risk reduction of mortality, ranging from nonexistent to statistically significant, plus the false positives and overdiagnosis that have limited establish their net profit.


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