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2020, Number 2

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Med Crit 2020; 34 (2)

Factors associated with mortality in the elderly adult with septic shock

González EEA, Sánchez DJS, Solórzano GA, Peniche MKG, Villegas DJE, Calyeca SMV

Language: Spanish
References: 45
Page: 125-132
PDF size: 308.55 Kb.


ABSTRACT

Introduction: By 2050 the elderly population worldwide for the first time in history will be greater than the young population. The incidence of septic shock is 13 times more common in patients › 65 years, knowing the risk factors associated with mortality in this population is essential for therapeutics.
Material and methods: Ambispective, longitudinal, descriptive, analytical study. Patients with a diagnosis of septic shock according to the consensus Sepsis-3 admitted to the ICU from June 1, 2015 to June 31, 2019. They were classified in the groups: 65 years, demographic, hemodynamic variables were included (index modified shock, SvcO2, Δp (va) CO2 /Δp (av) O2, BNP, vasopressor), respiratory (PaO2 /FiO2), metabolic (pH, HCO3- DB) and renal to compare them between both groups; the group › 65 years was subclassified according to the outcome in living and non-living to identify the variables with statistical value for it; descriptive statistics, χ2 and exact test of Fisher and t-Student and U-Mann-Whitney were used according to the case. A value of p ≤ 0.05 was considered significance and the program was used SPSS in version 20.
Results: 118 patients met the inclusion criteria. 78 patients in the group 65 years. Mortality in › 65 years was 67.5% versus 36% in 65 years, 27 patients died. The hemodynamic and respiratory variables had no statistical significance; unlike pH (p = 0.037), base (p = 0.041) and norepinephrine (p = 0.03).
Conclusion: Patients › 65 years of age have greater severity and comorbidity compared to younger patients. The hemodynamic and respiratory variables do not influence the outcome; severe metabolic acidosis is a risk factor for mortality in patients › 65 years.


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