Sosa CLE, Silva AAI, Rivera ME

Language: Spanish
References: 30
Page: 123-128
PDF size: 1046.99 Kb.

ABSTRACT

Mycobacterial infections in surgical procedures have a low incidence, but are cause of high complication and poor surgical success.
Objective. To evaluate antibiotic treatment with clarithromycin and levofloxacin in patients infected by Mycobacterium fortuitum in a plastic surgery procedure.
Material and method. 12 cases of patients infected with M. fortuitum in a surgical procedure for the placement of breast prostheses and/or abdominal mesh are reported. Patients were treated with clarithromycin 500 mg every 12 hours and levofloxacin 500 mg every 24 hours for 12 weeks, in addition to the removal of prosthetic material.
Results. After antibiotic treatment and removal of prosthetic material, patients presented clinical improvement and healing of the infection.
Conclusions. The use of antibiotic scheme with clarithromycin and levofloxacin for 12 weeks, in addition to the removal of the prosthetic material, resulted in healing of the infectious process caused by M. fortuitum.

REFERENCES

1. García Martos, P. y García Agudo, L., “Infecciones por micobacterias de crecimiento rápido”, Enferm Infecc Microbiol Clin 2012, 30 (4): 192-200.

2. Hypolite, T., Grant, J. y Chirch, L., “Nontuberculous mycobacterial infections: a potential complication of cosmetic procedures”, Int J Womens Dermatol, 2015, 1 (1): 51-54.

3. Regnier, S., Martínez, V., Veziris, N. et al., “Traitment des infections cutanées à Mycobacterium fortuitum: deux cases”, Ann Dermatol et Vénéréologie, 2008, 135 (8): 591-595.

4. Quiñones, C., Ramalle-Gómara, E., Perucha, M. et al., “An outbreak of Mycobacterium fortuitum cutaneous infection associated with mesotherapy”, jeadv, 2010, 24: 604-606.

5. Gracia-Cazaña, T., Milagro, A., Queipo, F. et al., “Mycobacterium fortuitum infection after acupunture treatment”, Dermatol Online J, 2017, 19, 23 (9).

6. Neill, B., Bahr, N., Bryan, Z. y Aires, D., “Cutaneous infection with Mycobacterium fortuitum after subcutaneous injection of human chorionic gonadotropin”, Dermatol Online J, 2017, 23 (8): 18.

7. Washer, L. y Gutowski, K., “Breast implant infections”, Infect Dis Clin N Am, 2012, (26): 111-125.

8. Cicilione, O., Foles, V., Sieger, B. et al., “Mycobacterium infection and red breast syndrome”, Plast Reconstr Surg Glob Open, 2013, 1: e50.

9. Uslan, D., Kowalsi, T., Wegenack, N. et al., “Skin and soft tissue infections due to rapidly growing mycobacterial”, Arch Dermatol, 2006, 142: 1287-1292.

10. Santos, A., Cremades, R., Rodríguez, J.C. et al., “Activity of various drugs alone or in combination against Mycobacterium fortuitum, J Infect Chemoter, 2010, 16: 64-67.

11. Shah, A., Gambhir, R., Hazra, N. y Katoch, R., “Non tuberculous mycobacteria in surgical wounds: a rising cause of concern?”, Indian J Surg, 2010, 72: 206-210.

12. Kim, H.R., Yoon, E.S., Kim, D.W., Hwang, N.H. et al., “Empirical treatment of highly suspected nontuberculous mycobacteria infections following aesthetic procedures”, Arch Plast Surg, 2014, 41 (6): 759-767.

13. Le Dantec, C., Duguet, J.P., Montiel, A. et al., “Ocurrence of mycobacteria in water treatment lines and in water distribution systems”, Appl Environ Microbiol, 2002, 68 (11): 5318-5325.

14. Sood, G. y Parrish, N., “Outbreaks of nontuberculous mycobacterial”, Curr Opin Infect Dis, 2017, 30: 404-409.

15. Hall-Stoodley, L. y Lappin-Scott, H., “Biofilm formation by the rapidly growing mycobacterial species Mycobacterium fortuitum”, fems Microbiol, 1988, 168: 77-84.

16. Faria, S., João, I. y Jordao, L., “General overview of nontuberculous mycobacteria, biofilms and human infection”, J Pathog, 2015, 2015: 809014.

17. Sousa, S., Bandeira, M., Carvalho, P.A., Duarte, A. y Jordão, L., “Nontuberculous mycobacteria pathogenesis and biofilm assembly”, Int J Mycobacteriol, 2015, 4: 36-43.

18. Ajdic, D., Zoghbi, Y., Gerth, D. et al., “The relationship of bacterial biofilms and capsular contracture in breast implants”, Aesthet Surg J, 2016, 36 (3): 297-309..

19. ATS Mycobacterial Diseases Subcommittee et al., “An official ats/idsa statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases”, Am J Resp Critical Care Med, 2007, 175 (4): 367-416.

20. Phadke, V., Hirsh, D. y Goswami, N., “Patient report and review of rapidly growing myocbacterial infection after cardiac device implantation”, Emerg Infect Dis, 2016, 22: 389-395.

21. Bengualid, V., Singh, V., Singh, H. y Berger, J., “Mycobacterium fortuitum and anaerobic breast abscess following nipple piercing: case presentation and review of the literature”, J Adol Health, 2008, 42; 530-532.

22. Shah, M., Relhan, N., Kuriyan, A. et al., “Endophtalmitis caused by nontuberculous mycobacterium: clinical features, antimicrobial susceptibilities, and treatment outcomes”, Am J Ophtalmol, 2016, 168: 150-156.

23. Set, R., Rokade, S., Agrawal, S. Shastri, J., “Antimicrobial susceptibility testing of rapidly growing mycobacteria by microdilution: experience of a tertiary care centre”, Indian J Med Microbiol, 2010, 28: 48-50.

24. Shen, Y., Wang, X., Jin, J., Wu, J., Zhang, X., Chen, J. y Zhang, W., “In Vitro susceptibility of mycobacterium abscessus and Mycobacterium fortuitum isolates to 30 antibiotics”, Biomed Res Int, 2018, 2018: 4902941.

25. Jayasingam, S.D., Thaw, Z. y Ngeow, Y.F., “Antibiotic resistance in Mycobacterium abscessus and Mycobacterium fortuitum isolates from Malaysian patients”, Int J Mycobacteriol, 2017, 6: 387-390.

26. Forbes, B.A., Hall, G.S., Miller, M.B., Novak, S.M., Rowlinson, M.-C., Salfinger, M., Somoskövi, A., Warshauer, D.M. y Wilson, M.L., “Practice guidelines for clinical microbiology laboratories: mycobacteria”, Clin Microbiol Rev, 2018, 31: e00038-17.

27. Schcolnik, A., Hernández, R., Vega, M. et al., “Lipotransferencia complicada con micobacterias atípicas. Reporte de dos casos y revisión de la literatura”, Gaceta Médica de México, 2014, 150 suppl 3: 311-316.

28. Lim, J.M., Kim, J.H. y Yang, H.J., “Management of infections with rapidly growing mycobacteria after unexpected complications of skin and subcutaneous surgical procedures”, Arch Plast Surg, 2012, 39: 18-24.

29. Macadam, S., Mehling, B., Fanning, A. et al., “Nontuberculous mycobacterial breast implant infections”, Plast Reconstr Surg, 2007, 119 (1): 337-344.

30. Al-Halabi, B., Viezel-Mathieu, A., Shulman, Z. et al., “Breast implant mycobacterial infections: an epidemiologic review and outcome analysis”, Plast Reconstr Surg, 2018, 142 (5): 639e-652e.