2020, Number 02
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Ginecol Obstet Mex 2020; 88 (02)
Maternal and neonatal outcomes in advanced maternal age
Santa María-Ortiz J, Álvarez-Silvares E, Alves-Pérez MT, García-Lavandeira S
Language: Spanish
References: 65
Page: 80-91
PDF size: 217.82 Kb.
ABSTRACT
Objective: To describe the maternal and perinatal results in pregnant women with
advanced age.
Materials and Methods: A cohort study was conducted with prospective
follow-up and retrospective data collection of the Clinical History of the University
Hospital Complex of Ourense between 2017 and 2018. Two cohorts were
established, cohort A with age greater than and equal to 40 years and the cohort
B with age under 40 years. Parametric and non-parametric tests were performed
to determine the potential association between the study variables (Chi-Square,
Student's T, Mann-Whitney U).
Results: The cohort A patients (n = 207) presented with statistical significance: body
mass index higher at the beginning of pregnancy (p = 0.028), higher number of previous
pregnancies (p = 0.001), but at the expense of a higher number of abortions (p
‹0.001), hypertensive states of pregnancy (p = 0.03), prematurity (p = 0.009), intrauterine
growth retardation (p = 0.006), fetal macrosomia (p = 0.04), inductions (p ‹ 0.001), of
both scheduled and intrapartum caesarean sections and postpartum hemorrhage (p =
0.001). No differences were found in parity, amenorrhea at delivery, pregestational /
gestational diabetes, mean fetal weight, Apgar score, umbilical artery pH and number
of newborns who required admission to the Neonatal Unit.
Conclusions: Advanced maternal age is an important risk factor for maternal and
perinatal morbidity. The higher rate of complications described reflects the importance
of thorough pregnancy control and careful peripartum surveillance.
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