2019, Number 2
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Sal Jal 2019; 6 (2)
Prevalencia de daño renal en pacientes de reciente diagnóstico con infección por VIH sin experiencia con antirretrovirales (naïve)
Corona-Ruiz F, Rodríguez-Toledo A, Rodríguez-Ruiz JA
Language: Spanish
References: 20
Page: 110-115
PDF size: 230.77 Kb.
ABSTRACT
Chronic kidney disease (CKD) is a significant cause
of morbidity in patients infected with the Acquired
Immune Deficiency Virus (HIV). The prevalence
of CKD in patients with HIV is estimated between
5-30%. There are factors that can influence the
development of kidney damage such as low CD4 +
lymphocytes or high blood virus values. This affects
the decision of the initial treatment.
Objective:
Relate renal function in patients with HIV infection
inexperienced antiretroviral (naïve) with levels of CD4
+ lymphocytes.
Materials and Methods: The present
study is a prevalence study, which is a descriptive,
retrospective cross-sectional design. General variables
sex and age of patients. Analytical variables such as
CD4 +, viral load, urea, and creatinine.
Results: A 119
patients were included, 93.2% of male, the average
age was 32 years, mean creatinine 0.87 mg/dL, mean
Urea 24.4 mg/dL, eGFR CKD-EPI average 112 mL/
min/1.73m
2, CD4 + on average 363 mm
3 cells and
viral load average 334.671 copies/ml. Proteinuria in
16.6% of patients. The prevalence of 14.8% of the
renal damage was found. The association of kidney
damage with low CD4 + counts P = 0.0001. There is
also an association with high viral load. P = 0.0001.
Conclusions: The prevalence of renal damage was
moderate. It is important always to a scrutiny of
kidney damage in patients diagnosed with HIV.
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