medigraphic.com
ISSN 1561-302X (Print)

2018, Number 4

<< Back Next >>

Rev cubana med 2018; 57 (4)

Obesity and mortality in chronic heart failure patients

Chao PC

Language: Spanish
References: 28
Page: 1-16
PDF size: 372.58 Kb.


ABSTRACT

Introduction: Obesity causes heart failure by different mechanisms that are not limited to traditional mediating factors. This is associated with inflammatory mechanisms, endothelial dysfunction and thrombogenic factors. In secondary prevention, an inverse effect of obesity was observed in the prognosis of patients with chronic HF. This phenomenon is known as the obesity paradox.
Objective: To update knowledge about obesity and its association with prognosis in relation to mortality in patients with chronic heart failure.
Method: A non-systematic review of the most significant studies on the subject was carried out, which were published in PUBMED, EBSCO, Scopus, Cochrane and the Cuban Journal of Internal Medicine.
Conclusions: Obesity offers prognostic information in relation to mortality in patients with chronic heart failure. Patients with obesity and overweight have lower mortality compared to normal weight.


REFERENCES

  1. Kovell LC, Juraschek SP, Russell SD. Stage a heart failure is not adequately recognized in US adults: analysis of the national health and nutrition examination surveys. 2007-2010. Plos One. 2015;10(7):e0132228. PubMed:PMID:26171960.

  2. Manzano L, Babalis D, Roughton M, Shibata M, Anker SD, Ghio S, et al. Predictors of clinical outcomes in elderly patients with heart failure. Eur J Heart Fail. 2011;13:528-36. PubMed:PMID: 21454299.

  3. Cuba. Ministerio de Salud Pública. Anuario Estadístico de Salud 2016. La Habana: Dirección nacional de Estadística y Registros Médicos; 2017.

  4. Block JP, Subramanian SV, Christakis NA, O’Malley AJ. Population trends and variation in body mass index from 1971 to 2008 in the Framingham heart study offspring cohort. Plos One. 2013;8(5):e63217.

  5. Nicholson C. Chronic heart failure: pathophysiology, diagnosis and treatment. Nurs Older People. 2014;26:29-38. PubMed:PMID:25171366.

  6. Horwich TB, Fonarow GC, Hamilton MA, MacLellan WR, Woo MA, Tillisch JA. The relationship between obesity and mortality in patients with heart failure. J Am Coll Cardiol. 2001;38:789-95. PubMed:PMID:11527635.

  7. Haehling S, Horwich T, Fonarow G, Anker S. Tipping the scale: heart failure, body mass index, and prognosis. Circulation. 2007;116:588-90.

  8. Alfonzo Guerra JP. Retos de la paradoja mayores riesgos y más expectativa de vida vs realidad en la salud. Rev Cub Med. 2016[acceso: 2/02/2018];55:159-66. Disponible en: http://bvs.sld.cu/revistas/med/vol55_2_16/med07216.htm

  9. Serna F de la. Insuficiencia cardiaca crónica. 3ra ed. Argentina: Federación Argentina Cardiología; 2010 [acceso: 22/08/2014]. Disponible en: http://www.fac.org.ar/1/publicaciones/ libros/inscard.php

  10. Clerico A, Giannoni A, Vittorini S, Emdin M. The paradox of low BNP levels in obesity. Heart Fail Rev. 2012;17:81-96. PubMed:PMID:21523383.

  11. Qin W, Liu F, Wan C. A U-shaped association of body mass index and all-cause mortality in heart failure patients: a dose-response meta-analysis of prospective cohort studies. Cardiovasc Ther. 2017;35:e12232. PubMed:PMID:27783461.

  12. Hong S, Lee JH, Kim KM, Lee JW, Youn YJ, Ahn MS, et al. Is there a sex-related difference in the obesity paradox in systolic heart failure? Sex-related difference in the obesity paradox. Yonsei Med J. 2018;59:57-62.

  13. Deswal A, Petersen NJ, Feldman AM, Young JB, White BG, Mann DL. Cytokines and cytokine receptors in advanced heart failure: an analysis of the cytokine database from the vesnarinone trial (VEST). Circulation. 2001;103:2055-9.

  14. Feldman AM, Combes A, Wagner D, Kadakomi T, Kubota T, Li YY, et al. The role of tumor necrosis factor in the pathophysiology of heart failure. J Am Coll Cardiol. 2000;35:537-44.

  15. Zaninović T, Dvornik S, Jurjević N, Lekić A, Zaputović L. The correlation between body mass index, routine clinical and laboratory parameters and in-hospital survival in patients with acutely decompensated heart failure. Cardiol Croat. 2017 [acceso: 20/05/2015];12(9-10):362. Disponible en: https://www.kardio.hr/pdf/Cardiologia%20 croatica% 202017%2012_910_362.pdf

  16. Curtis JP, Selter JG, Wang Y, Rathore SS, Jovin IS, Jadbabaie F, et al. The obesity paradox: body mass index and outcomes in patients with heart failure. Arch Intern Med. 2005;165:55-61. PubMed:PMID: 25772740.

  17. Karas MG, Benkeser D, Arnold AM, Bartz TM, Djousse L, Mukamal KJ, et al. Relations of plasma total and high-molecular-weight adiponectin to new-onset heart failure in adults ≥ 65 years of age (from the Cardiovascular Health Study). Am J Cardiol. 2014;113:328e-34. PubMed:PMID: 24169012.

  18. Fernández A, Ferrante D, Hrabar A, Soifer S, Varini S, Nul D, et al. Valor pronóstico del índice de masa corporal en pacientes con insuficiencia cardíaca crónica: Registro GESICA. Rev Argent Cardiol. 2006[acceso: 20/05/2015];74:204-10. Disponible en: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1850-37482006000400005

  19. Oreopoulos A, Padwal R, Kalantar Zadeh K, Fonarow GC, Norris CM, McAlister FA. Body mass index and mortality in heart failure: a meta-analysis. Am Heart J. 2008;156:13-22.

  20. Trullas JC, Formiga F, Montero M, Conde A, Casado J, Carrasco F J, et al. Paradoja de la obesidad en la insuficiencia cardiaca. Resultados del registro RICA. Med Clin (Barc). 2011;137:671-7.

  21. Trullas JC, Formiga F, Montero M, Conde A, Casado J, Carrasco FJ, et al. Paradoja de la obesidad en la insuficiencia cardiaca. Resultados del registro RICA. Med Clin (Barc). 2011;137:671-7.

  22. Khalid U, Ather S, Bavishi C, Chan W, Loehr LR, Wruck LM, et al. Pre-morbid body mass index and mortality after incident heart failure: the ARIC Study. J Am Coll Cardiol. 2014;64:2743-9. PubMed PMID: 255411

  23. Shah R, Gayat E, Januzzi JL, Sato N, Cohen-Solal A, Disomma S, et al. Body mass index and mortality in acutely decompensated heart failure across the world: a global obesity paradox. J Am Coll Cardiol. 2014;63:778-85. PubMed: PMID: 24315906.

  24. Littnerova S, Parenica J, Spinar J, Vitovec J, Linhart A, Widimsky P, et al. Positive influence of being overweight/obese on long term survival in patients hospitalised due to acute heart failure. PLoS One. 2015;10:e0117-42. PubMed PMID: 25710625.

  25. Sharma A, Lavie CJ, Borer JS, Vallakati A, Goel S, Lopez Jiménez F, et al, Meta-analysis of the relation of body mass index to all-cause and cardiovascular mortality and hospitalization in patients with chronic heart failure. Am J Cardiol. 2015;115:1428-34. PubMed:PMID: 25772740.

  26. Matsushita M, Shirakabe A, Hata N, Shinada T, Kobayashi N, Tomita K, et al. Association between the body mass index and the clinical findings in patients with acute heart failure: evaluation of the obesity paradox in patients with severely decompensated acute heart failure. Heart Vessels. 2017;32:600-8. PubMed:PMID:27778068

  27. Chao Pereira C, Rojas Gutiérrez A, Roselló Azcanio Y, Andre Tiago. Influencia del índice de masa corporal en la mortalidad de pacientes con insuficiencia cardiaca. Rev Cubana Med. 2017 [acceso: 22/04/2017];56(3).

  28. Zamora E, Díez López C, Lupón J, de Antonio M, Domingo M, Santesmases J, et.al. Weight loss in obese patients with heart failure. J Am Heart Assoc. 2016;5(3):e002468. PubMed:PMID:27013541.




2020     |     www.medigraphic.com