2019, Number 11
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Ginecol Obstet Mex 2019; 87 (11)
Acute transfusion-related lung injury (TRALI) in pregnancy. Case report and bibliographic review
Rafaelano-Miranda AJ, Morales-Flores I, Tolentino-Sosa MI, Barbabosa-Vilchis JA
Language: Spanish
References: 23
Page: 747-755
PDF size: 583.73 Kb.
ABSTRACT
Background: Transfusion-related acute lung injury (TRALI) is a syndrome of respiratory
distress caused by blood transfusion. The Food and Drug Administration (FDA)
places TRALI as the main cause of death associated with transfusion.
Objective: The present clinical case is reported, treated in a Third Level Hospital
and a search was carried out to update the topic on the management of TRALI in a
pregnant patient.
Clinical case: A 35-year-old woman with a pregnancy of 33.2 weeks of gestation,
placental accreta, with a threat of preterm delivery and severe anemia that required
hemotransfusion of erythrocyte concentrate, subsequently with a respiratory distress
syndrome clinic. TRALI was diagnosed, it was managed in intensive therapy with
diuretic and inotropic, it evolved clinically to the improvement, until its total improvement,
Placental accreta was corroborated, cystoscopy was performed without data on
bladder invasion. Subsequently, he presented uterine activity and premature rupture
of membranes, caesarean section and obstetric hysterectomy were performed. The
patient evolved satisfactorily and left without incident.
Conclusions: There are very few documented reports of TRALI in the period prior
to delivery. Pregnant women are disadvantaged by the physiological changes of preg-
nancy such as decreased residual volume and respiratory reserve capacity, decreased
capillary colidosidotic pressure. Therefore, the diagnosis of TRALI is important to
manage timely management. The management of respiratory failure in TRALI must be
done multidisciplinary way.
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