Roque-Fernández MÁ, González-Mirasol E, Álvarez-Lleó C, Sánchez-Toledo M, García-Garrido C, Amezcua-Recover A

Language: Spanish
References: 28
Page: 740-746
PDF size: 323.57 Kb.

ABSTRACT

Objective: To investigate the relationship between serum progesterone level on the day of oocyte retrieval and pregnancy outcomes in patients undergoing IVF.
Materials and Methods: Prospective cohort study of IVF-ICSI cycles, with long or antagonistic agonist protocol and with fresh embryo transfer on day 2-3. We proposed a serum progesterone level on p90 on day of oocyte retrieval. The main outcome analysed are biochemichal and clinical pregnancy and first trimester miscarriage.
Results: 400 cycles of IVF-ICSI were studied, with long agonist protocol (n = 41) or antagonist (n = 359) and with fresh embryo transfer on day 2-3. Pregnancy rate was similar in both groups (41 vs 40.2%) and clinical pregnancy rate was lower (30.8 vs 33.5%), but it wasn’t statically significance. There was more miscarriage in elevation progesterone group (25.7 vs 43.8%), but it wasn´t statiscally significance.
Conclusion: Progesterone elevation on oocyte retrieval are not associated with the IVF outcome, but there is a trend to lower clinical pregnancy and more miscarriages.

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