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ISSN 0210-5187 (Electronic)

2006, Number 2

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Med Cutan Iber Lat Am 2006; 34 (2)

Conjunctival melanoma: a case report and review of the literature

Molgó NM, Bustamante CS, Silva PP, González BS, Flores PJC

Language: Spanish
References: 12
Page: 71-76
PDF size: 222.39 Kb.


ABSTRACT

Conjunctival melanomas arise from the same embriologically derived melanocytes as their cutaneous counterparts. However, ocular and cutaneous melanomas differ in its clinical presentation, epidemiology, treatment and prognosis. Conjunctival melanoma has an extremelly low incidence. In the last years an increasing number of cases has been reported. Most of conjunctival melanomas develop in the limbus or the bulbar conjunctiva, from conjunctival nevi, primary acquired melanosis or “de novo”.
Any pigmented lesion arising in palpebral conjunctiva should be considered as probable melanoma, because seldom a benign lesion arises at this site. Although the treatment relies principally on the ophthalmologist.


REFERENCES

  1. Grin JM, Grant-Kels JM, Grin CM, Berke A, Kels BD. Ocular melanomas and melanocytic lesions of the eye. J Am Acad Dermatol 1998;38:716-30.

  2. Shields CL, Shields JA, Gündüz K, Cater J, Mercado GV, Gross N, Rally B. Conjuntival melanoma. Risk factors for recurrence, exenteration, metastasis, and death in 150 consecutive patients. Arch Ophthalmol 2000;118:1497-507.

  3. Char DH. Ocular melanoma. Surg Clin North Am 2003;83:253-74.

  4. Farber M, Schutzer P, Mihm MC. Pigmented lesions of the conjuntiva. J Am Acad Dermatol 1998;38:971-8.

  5. Yu G, Hu D, McCormick S, Finger PT. Conjuntival melanoma: is it increasing in the United Sates? Am J Ophthalmol 2003;135: 800-6.

  6. Chang AE, Kernell LH, Menck HR. The national cancer data base report on cutaneous and noncutaneous melanoma: a summary of 84836cases from the past decade. Cancer 1998;83:1664-78.

  7. Vajdic CM, Kricker A, Giblin M, McKenzie J, Aitken J, Giles GG, Armstrong BK. Sun exposure predicts risk of ocular melanoma in Australia. Int J Cancer 2002;101:175-82.

  8. Vajdic CM, Kricker A, Giblin M, McKenzie J, Aitken J, Giles GG, Armstrong BK. Eye color and cutaneous nevi predict risk of ocular melanoma in Australia. Int J Cancer 2001; 92:906-12.

  9. Demirci H, Shields CL, Shields JA, Tagle RC. Malignant melanoma arising from unusual conjuntival blue nevus. Arch Ophthalmol 2000;118:1581-4.

  10. Shields CL, Shields JA, Armstrong T. Management of conjuntival and cormeal melanoma with surgical excision, amniotic membrane allograft, and topic chemotherapy. Am J Ophthalmol 2001; 132:576-8.

  11. Demirci H, McCormick SA, Finger PT. Topical mitomycin chemotherapy for conjuntival malignant melanoma and primary acquired melanosis with atypia: clinical experience with histopathologic observations. Arch Ophthalmol 2000;118:885-91.

  12. Esmaeli B, Eicher S, Popp J, Delpassand E, Prieto VG, Gershenwald JE. Sentinel lymph node biopsy for conjuntival melanoma. Ophthalmic Plast Reconstr Surg 2001; 17436-442.




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