2018, Number 4
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Rev Cub Oftal 2018; 31 (4)
Clinical and pathological characterization of uveal melanoma
Fernández GO, Abreu PFA, Hernández PA, Santos SD, Ortiz RDL, Rojas RI
Language: Spanish
References: 19
Page: 17-24
PDF size: 210.03 Kb.
ABSTRACT
Objective: To describe the clinical and pathological characteristics of patients diagnosed with uveal melanoma.
Methods: A retrospective, descriptive and case series study was performed from January 2011 to June 2016 in the Institute of Oncology and Radiobiology of Cuba (INOR). The universe of study was the sample of 41 patients, all of them diagnosed with uveal melanoma and treated in this period of time. The study variables were age, sex, laterality, tumor location and tumor, classification, cell type, degree of invasion and treatment.
Results: Females accounted for 56.1 % of the sample. The patients aged 50 years or over (75.6 %) were the most affected whereas left eye was the most vulnerable (58.5 %). The main location were the choroids (75.6 %) According to size, the large tumors predominated (58.5 %); from the histological viewpoint, the most common cell-type was fusiform cell tumor (34.2 %); according to the degree of invasion, the sclera was the most affected (17 %) and the only treatment was enucleation.
Conclusions: Uveal melanoma is more frequently located in the choroids. It mainly appears in patients aged over 50 years and most of tumors are large.
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