2019, Number 5
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Rev Fac Med UNAM 2019; 62 (5)
Genetically modified T lymphocytes: A new hope for glioblastoma treatment?
Choreño PJA, Guadarrama OP
Language: Spanish
References: 7
Page: 7-10
PDF size: 339.11 Kb.
ABSTRACT
Glioblastoma is among the most aggressive primary tumors
of the central nervous system due to its high capacity to
acquire resistance to many of the currently available oncologic
treatments. Likewise, this tumor possesses an elevated
potential for recurrence generating a high mortality among
affected individuals. Therefore, there is an urgent necessity for
new therapeutic strategies to achieve a higher remission rate
and a better survival rate in patients with glioblastoma. New
advances in immunotherapy, such as the production of autologous
T lymphocytes modified by genetic engineering, are
promissory therapeutic agents capable of providing a considerable
degree of control over different types of cancers.
In this article, we discuss the results of some recent studies
on the specific use of this strategy for the management of
individuals with glioblastoma.
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