2019, Number 3
Neurodevelopment follow up to late preterm new burns until two years old
Language: Spanish
References: 32
Page: 1-14
PDF size: 586.38 Kb.
ABSTRACT
Introduction: The late preterm newborns (LPN) present complications to short and long term that can affect their neurodevelopment.Objective: To evaluate the state of neurodevelopment in LPN until two years of age.
Methods: It was carried out a retrospective, observational, analytic and longitudinal study with 69 LPN admitted in the neonatal intensive cares unit of "Dr. Ángel Arturo Aballí" Hospital from March 2009 to December 2014 that were referenced to the neurodevelopment consultation. The obtained results were compared with a control group conformed by term newborns. The results were expressed in percentages.
Results: Masculine sex prevailed in both groups (65.2 % vs. 59.4 %) and the birth by Caesarean operation in the LPN (68.1 % vs. 39.9 % in the control group). LPN had bigger mechanical ventilation (52.2 % vs. 23.2 %) and of anti-seizure drugs use’s needs (13.0 % vs. 5.8 %). It was observed a greater incidence of neurodevelopment alterations in the LPN to 6 months old (18.8 % vs. 15.9 %), 1-year-old (8.7 % vs. 7.2 %) and 2 years olds (7.7 % vs. 2.3 %). In the studies, bigger incidence of abnormal results was observed in transfontanelle ultrasonography (7.2 % vs. 2.9 %), auditory evoked potentials of cerebral stem (14.5 % vs. 1.4 %) and in ocular fundus (4.3 % vs. 1.4 %).
Conclusions: The birth by Caesarean section predominated in the LPN that is why they needed mechanical ventilation and resuscitation at birth. This group presented more affectation of the neurodevelopment state than the control group and bigger risk of hearing loss.
REFERENCES
Granese R, Mantegna S, Mondello S, Amadore D, Imbesi G,Calagna G, et al. Preterm birth: incidence, risk factors and second trimester cervical length in a single center population. A two-year retrospective study. Eur Rev Med Pharmacol Sc. 2017;21. Access: 2017/12/12. Available at: http://www.europeanreview.org/wp/wp-content/uploads/4270-4277-Preterm-birth-in-a-single-center population.pdf
Stacy Beck DW, Lale Say AP, Merialdi M, Harris Requejo J, Rubens C, Menon R, et al. Incidencia mundial de parto prematuro: revisión sistemática de la morbilidad y mortalidad maternas. Bull World Health Organization. 2010;88(1). Acceso:15/12/2016. Disponible en: http://www.who.int/bulletin/volumes/88/1/08-062554-ab/es/
Johnson S, Evans TA, Draper ES, Field DJ, Manktelow BN, Marlow N, et al. Neurodevelopmental outcomes following late and moderate prematurity: a population-based cohort study. Arch Dis Child Fetal Neonatal Ed. 2015;100. Access: 2016/04/12. Available at: http://fn.bmj.com/content/100/6/F479.full.pdf+html
Robaina Castellanos GR, Santiago López AM, Riesgo Rodríguez S de la C, Rodríguez del Toro N. Epidemiología de la encefalopatía neonatal en un hospital de tercer nivel en Cuba. Rev Cubana Pediatr. 2013;85(1). Acceso: 12/04/2016. Disponible en: http://scielo.sld.cu/scielo. php?script=sci_pdf&pid=S0034-75312013000100006&lng=es&nrm=iso&tlng=es
Farzam P, Buckley EM, Lin P-Y, Hagan K, Grant PE, Inder TE, et al. Shedding light on the neonatal brain: probing cerebral hemodynamics by difuse optical spectroscopic methods. Scientific Rep. 2017;7:15786. Access: 2017/12/12. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693925/pdf/41598_2017_Article_15995.pdf
Cheong JL, Doyle LW, Burnett AC, Lee KJ, Walsh Cody JM, Potter R, et al. Association between Moderate and Late Preterm Birth and Neurodevelopment and Social-Emotional Development at Age 2 Years. JAMA Pediatr. 2017;10:1001. Access: 2017/09/06. Available at: http://jamanetwork.com/article.aspx?doi=10.1001/jamapediatrics.2016.4805
Janér C, Pitkänen OM, Süvari L, Turpeinen U, Palojärvi A, Andersson S, Helve O. Duration of Gestation and Mode of Delivery Affect the Genes of Transepithelial Sodium Transport in Pulmonary Adaptation. Neonatology 2015;107. Access: 2016/02/18. Available at: https://www.karger.com/Article/FullText/363729
Boyle EM, Johnson S, Manktelow B, Seaton SE, Draper ES, Smith LK, et al. Neonatal outcomes and delivery of care for infants born late preterm or moderately preterm: a prospective population-based study. Arch Dis Child Fetal Neonatal Ed. 2015;100:(6). Access: 2016/04/15. Available at: http://fn.bmj.com/content/100/6/F479.long
Polić B, Bubić A, Meštrović J, Markić J, Kovačević T, Furlan AI, et al. Emotional and behavioral outcomes and quality of life in school-age children born as late preterm: retrospective cohort study. Croat Med J. 2017;58. Access: 2016/04/15. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740154/pdf/41598_2017 Article_18371.pdf 18. Shaikh N, Faizi S, Rai L. Respiratory Morbidity in Late-Preterm Births: A Prospective Observational Study at a Tertiary Care Hospital. J Obstet Gynaecol India. 2016;66(Suppl. 1). Access: 2017/02/20. Available at: https://www.ncbi.nlm.nih.gov/pmc/ articles/PMC5016472/pdf/13224_2016_Article_893.pdf
Schwaberger B, Pichler G, Binder-Heschl C, Baik-Schneditz N, Avian A, Urlesberger B. Cerebral Blood Volume During Neonatal Transition in Term and Preterm Infants With and Without Respiratory Support. Front Pediatr. 2018;6(132). Access: 2018/06/02. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945863/
Simon L, Théveniaut C, Flamant C, Frondas-Chauty A, Darmaun D, Rozé JC. In Preterm Infants, Length Growth below Expected Growth during Hospital Stay Predicts Poor Neurodevelopment at 2 Years. Neonatology. 2018;114. Access: 2018/06/03. Available at: https://www.karger.com/Article/FullText/487663 26. Kugelman A, Colin AA. Late Preterm Infants: Near Term But Still in a Critical Developmental Time Period. Pediatrics. 2013;132 (4). Access: 2017/10/03. Available at: http://pediatrics.aappublications.org/content/132/4/741.full-text.pdf
Allvin K, Hellström A, Dahlgren J, Grönlund MA. Birth weight is the most important predictor of abnormal retinal vascularization in moderately preterm infants. Acta Pædiatric. 2014;103:594-600. 31. Szyfter W, Wrobel MJ, Szyfter-Harris J, Greczka G. Hearing impairment in Polish infants. Epidemiology. 2013;24(2). Access: 2017/10/03. Available at: https://www.ncbi.nlm. nih.gov/pubmed/23377094
Wroblewska-SeniukK, Greczka G, Dabrowski P, Szyfter-Harris J, Mazela J. Hearing impairment in premature newborns-Analysis based on the national hearing screening database in Poland. PLoS One. 2017;12(9). Access: 2017/10/03. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598959/pdf/pone.0184359.pdf