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2019, Number 3

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Rev Cubana Pediatr 2019; 91 (3)

Idiopathic hypercalciuria as predisposing factor of urinary infection

Adrian CM, Durán ÁS, Irisarry RG, Hernández HJS, Sosa PO

Language: Spanish
References: 25
Page: 1-12
PDF size: 511.34 Kb.


ABSTRACT

Introduction: Idiopathic hypercalciuria is a relatively frequent metabolic alteration and there are scarce publications on its relation with the urinary tract´s infection.
Objective: To specify if there is a relation between urinary infection and idiopathic hypercalciuria, in order to determine if this last one constitutes a risk factor of urinary infection.
Methods: Prospective, descriptive and longitudinal study in pediatric age’s patients with a diagnosis of urinary infection that were attended in “William Soler” University Pediatric Hospital from January 1st, 2016 to December 31st, 2017. After two weeks of the infection being controlled, a urine sample from the first micturition of the day was collected to determine calcium/creatinine index and to specify calcium excretion in 24 hours. If this test shows positive results, after two to four weeks the sample is repeated, and if both are positive and calcium level in blood is normal, so idiopathic hypercalciuria is diagnosed.
Results: 130 patients were included in the study. In 43.8 % idiopathic hypercalciuria was found. 52.3 % were studied during the first infectious episode, and there is presented a history of infection or recurrence. In 86.2 % of the patients, the infection was catalogued as pyelonephritis. Hypercalciuria´s gender distribution didn’t show any differences, and the symptom called hematuria with recurrent abdominal pain was suggestive to an infection related to hypercalciuria (p < 0.05). The infectious germ does not induce to think in hypercalciuria.
Conclusions: Idiopathic hypercalciuria constitutes a predisposing factor of urinary tract’s infection.


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