2019, Number 4
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Bol Med Hosp Infant Mex 2019; 76 (4)
Zika as a cause of spontaneous abortion in endemic areas
Rivadeneyra-Espinar PG, Venegas-Esquivel GA, Díaz-Espinoza CM, Pérez-Robles VM, González-Fernández MI, Sesma-Medrano E
Language: Spanish
References: 20
Page: 193-197
PDF size: 80.19 Kb.
ABSTRACT
Background: Although in most cases Zika is an uncomplicated febrile disease, in pregnant women is a recognized cause
of congenital disorders. Microcephaly is the characteristic most frequently described in the congenital Zika virus syndrome,
and the diagnosis requires laboratory confirmation.
Case report: A 23-year-old female on the ninth week of pregnancy by
date of last menstrual period and 10.3 weeks by ultrasound, attended to Health Services, presenting clinical manifestations
of Zika infection, which was later confirmed by laboratory tests. In her 18.6 weeks of pregnancy, a non-mobile single fetus
was documented. Additional findings were microcephaly, lack of thorax with cardiac activity, anterior corporal placenta with
30% calcification, and an image of probable venous lake versus placental cyst. She was admitted to the emergency room for late abortion and labor was induced, obtaining an 80 g male product with head circumference of 9 cm. Reverse
transcription polymerase chain reaction analysis on the umbilical cord was positive for Zika virus.
Conclusions: Zika infection
during pregnancy must be suspected and diagnosed promptly to offer comprehensive care. The loss of conception in these
patients has been documented with results of chorionic villus biopsies, finding Zika virus RNA and suggesting spontaneous
abortion early during viremia.
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