2019, Number 1
<< Back Next >>
Rev Cub Med Mil 2019; 48 (1)
Clinical epidemiological characterization of patients operated on spinal cord tumors
Singuepire A, Figueredo AH, Fonseca SK
Language: Spanish
References: 29
Page: 56-66
PDF size: 226.72 Kb.
ABSTRACT
Introduction: Spinal cord tumors are the leading cause of morbidity and mortality among patients with oncological conditions and it represents approximately 10% to 15% of all tumors of the central nervous system.
Objective: To identify clinical and epidemiological aspects of patients operated on spinal cord tumors, from 2008 to 2013.
Methods: We conducted an observational, descriptive study of a series of cases in 31 patients older than 19 years at the Neurosurgery Service of Saturnino Lora Provincial Teaching Hospital in Santiago de Cuba from January 2008 to December 2013. The subjects had diagnosis of intratracheal tumors.
Results: In the cases studied (n = 31) age ranged 19 to 76 years. Female patients (54.8%) and benign lesions (64.5%) were the majority. The most frequent localization was dorsal and extradural in the spinal axis.
Conclusions: The main clinical and epidemiological characteristics were age of more frequent presentation of tumor lesions, that is 60 years of age; symptomatology with variable neurological involvement, spinal pain in all cases, and predominance of benign lesions.
REFERENCES
Sharma M, Sonig A, Ambekar S, Nanda A. Discharge dispositions, complications, and costs of hospitalization in spinal cord tumor surgery: analysis of data from the United States Nationwide Inpatient Sample, 2003-2010. J Neurosurg Spine. 2014;20:125-141.
Karhade AV, Vasudeva VS, Dasenbrock HH, Lu Y, Gormley WB, Groff MW. Thirty-day readmission and reoperation after surgery for spinal tumors: a National Surgical Quality Improvement Program analysis. Neurosurg Focus. 2016;41(13):[aprox. 20 pant.]. Access: 03/03/2018. Available from: http://thejns.org/doi/full/10.3171/2016.5.FOCUS16168
Greenberg MS. Manual de Neurocirugía. 2da edición. Buenos Aires: Ediciones Journal; 2013.
Bansal S, Ailawadhi P, Suri A, Kale SS, Sarat Chandra P, Singh M. Ten years' experience in the management of spinal intramedullary tumors in a single institution. J Clin Neurosci. 2013;20(2):292-8. Access: 03/03/2018. Available from: https://www.jocn-journal.com/article/S0967-5868(12)00351-7/fulltext
Pendleton C, Rincon-Torroella J, Gokaslan ZL, Jallo GI, Quinones-Hinojosa A. Challenges in early operative approaches to intramedullary spinal cord tumors: Harvey Cushing's perspective. J Neurosurg Spine. 2015;23:412-8. Access: 3/03/2018. Available from: http://thejns.org/doi/full/10.3171/2014.12.SPINE13427
Ogden AT, Schwartz TH, McCormick PC. Spinal Cord Tumors in Adults. En: Winn HR, editor. Youmans Neurological Surgery. Philadelphia: Elsevier;2011. p. 3131-43.
Karsy M, Guan J, Sivakumar W, Neil JA, Schmidt MH, Mahan MA. The genetic basis of intradural spinal tumors and its impact on clinical treatment. Neurosurg Focus. 2015;39(13):[aprox. 31 pant.]. Access: 03/03/2018. Available from: http://thejns.org/doi/full/10.3171/2015.5.FOCUS15143
Ottenhausen M, Ntoulias G, Bodhinayake I, Rupert FH, Schreiber S, Förschler A. Intradural spinal tumors in adults-update on management and outcome. Neurosurg Rev, 2018;41(1):1-18. Access: 03/03/2018. Available from: https://doi.org/10.1007/s10143-018-0957-x
Hirano K, Imagama S, Sato K, Kato F, Kawa Y, Yoshihara H. Primary spinal cord tumors: review of 678 surgically treated patients in Japan. A multicenter study Eur Spine J. 2012;21(10):2019-26.
Hernández Solarte A, Losada Díaz A, Ortega Campos LG. Estudio de la incidencia de tumores raquimedulares tratados en el servicio de neurocirugía hospital San Juan de Dios y revisión del tema. Neuroeje. 1999;13(3): 102-8. Acceso: 03/03/2018. Disponible en: http://www.binasss.sa.cr/revistas/neuroeje/v13n3/art7.pdf
Da Roza P. Primary intraspinal tumours: their clinical presentation and diagnosis. An analysis of ninety-five cases. J Bone Joint Surg Am. 2009;46:8-15.
Matsumoto M, Tsuji T, Iwanami A, Watanabe K, Hosogane N, Ishii K. Total in bloc spondylectomy for spinal metastasis of differentiated thyroid cancers: a long-term follow-up. Spinal Disord Tech. 2013;26(4): 137-42. Access: 3/03/2018] Available from: https://insights.ovid.com/crossref?an=00024720-201306000-00013#
Kaloostian PE, Zadnik PL, Etame AB, Vrionis FD, Gokaslan ZL, Sciubba DM. Surgical management of primary and metastatic spinal tumors. Cancer Contr. 2014;21:133-9.
Mesfin A, Buchowski JM, Gokaslan ZL, Bird JE. Management of metastatic cervical spine tumors. J Am Acad Orthop Surg. 2015;23:38-46.
Schairer WW, Carrer A, Sing DC, Chou D, Mummaneni PV, Hu SS. Hospital readmission rates after surgical treatment of primary and metastatic tumors of the spine. Spine 2014;39(21):1801-8. Access: 03/03/2018. Available from: https://journals.lww.com/spinejournal/Fulltext/2014/10010/Hospital_Readmission_Rates_After_Surgical.17.aspx
Zwagerman NT, McDowell MM, Hamilton RL, Monaco III EA, MD, Flickinger JC, Gerszten PC. Histopathological examination of spine tumors after treatment with radiosurgery. Neurosurg Focus. 2016;41(2):1-4. Access: 03/03/2018. Available from: http://thejns.org/doi/full/10.3171/2016.5.FOCUS16119
Loya JJ, Jung H, Temmins C, Cho N, Singh H. Primary spinal germ cell tumors: a case analysis and review of treatment paradigms. Case Rep Med. 2013(2013):[aprox. 16 scr ]. Access: 03/03/2018. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838823/
Molina CA, Sciubba DM. Tumors of the Spine. En: Baaj AA, Mummaneni PV, Uribe JS, Vaccaro AR, Greenberg MS. Handbook of Spine Surgery. New York: Thieme Medical Publishers, Inc; 2012.
Alpízar-Aguirre A, Chávez C, Zarate B, Rosales LM, Baena L, Reyes A. Tumores intradurales extramedulares primarios tratados en el instituto nacional de rehabilitación. Cir Ciruj. 2009;77:107-10. Acceso: 03/03/2018. Disponible en: http://www.medigraphic.com/pdfs/circir/cc-2009/cc092e.pdf
Claus E, Abdel-Wahab M, Burger PC, Engelhard H. Defining future directions in spinal cord tumor research: J Neurosurg Spine. 2010;12(2):117-21. Access: 03/03/2018. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193276/pdf/nihms-278450.pdf
Tobin MK, Geraghty JR, Engelhard HH, Linninger AA, Mehta AI. Intramedullary spinal cord tumors: a review of current and future treatment strategies. Neurosurg Focus. 2015;39(10):[aprox. 25 scr.]. Access: 03/03/2018. Available from: http://thejns.org/doi/full/10.3171/2015.5.FOCUS15158
Mc Cormick P. Intradural extramedullary tumors. En: Quiñones-Hinojosa A. Operative Neurosurgical Techniques Indications, Methods, And Results. Philadelphia: Elsevier; 2012. p. 2126-2133.
Ostrom QT, Gittleman H, Liao P, Rouse C, Chen Y, Dowling J. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. Neuro Oncol. 2014;16(Suppl 4):1-63.
Samuel N, Tetreault L, Santaguida C, Nater A, Moayeri N, Massicotte EM. Clinical and pathological outcomes after resection of intramedullary spinal cord tumors: a single-institution case series. Neurosurg Focus. 2016;41(2):1-8. Access: 03/03/2018. Available from: https://thejns.org/downloadpdf/journals/neurosurg-focus/41/2/article-pE8.pdf
Bakar D, Tanenbaum JE, Phan K, Alentado VJ, Steinmetz MP, Benzel EC. Decompression surgery for spinal metastases: a systematic review. Neurosurg Focus. 2016;41(2):1-35. Access: 03/03/2018. Available from: https://thejns.org/downloadpdf/journals/neurosurg-focus/41/2/article-pE2.pdf
He J, Xiao J, Peng X, Duan B, Li Y, Ai P. Dose escalation by image-guided intensity-modulated radiotherapy leads to an increase in pain relief for spinal metastases: a comparison study with a regimen of 30 Gy in 10 fractions. Oncotarget, 2017;8(68):112330-40. Access: 03/03/ 2018. Available from: http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=18979&path[]=60831
Sung WS, Sung MJ, Chan JH, Manion B, Song J, Dubey A. Intramedullary spinal cord metastases: a 20-year institutional experience with a comprehensive literature review. World Neurosurg. 2013;79:576-84.
Sun J, Wang Z, Li Z, Liu B. Microsurgical treatment and functional outcomes of multi-segment intramedullary spinal cord tumors. Clin Neurosci. 2009;16(5):666-71. Access: 03/03/2018. Available from: https://www.sciencedirect.com/science/article/pii/S0967586808004803?via%3Dihub
Guerrero-Suárez PD, Magdaleno-Estrella E, Guerrero-López P, Vargas-Figueroa AI, Martínez-Anda JJ. Intradural spinal tumors: 10 - years surgical experience in a single institution. Clin Neurol Neurosurg. 2018;169:98-102.