medigraphic.com
ISSN 1561-3046 (Digital)

2019, Número 1

<< Anterior Siguiente >>

Rev Cub Med Mil 2019; 48 (1)


Caracterización clínica epidemiológica de pacientes operados de tumores raquimedulares

Singuepire A, Figueredo AH, Fonseca SK

Idioma: Español
Referencias bibliográficas: 29
Paginas: 56-66
Archivo PDF: 226.72 Kb.


RESUMEN

Introducción: Los tumores raquimedulares son la mayor causa de morbilidad y mortalidad entre pacientes con afecciones oncológicas y representan aproximadamente del 10 al 15 % de todos los tumores del sistema nervioso central.
Objetivo: Identificar aspectos clínicos y epidemiológicos en pacientes operados de tumores raquimedulares.
Métodos: Se realizó un estudio observacional descriptivo, de serie de casos, en 31 pacientes de más de 19 años, operados/as de tumores intrarraquídeos, en el servicio de Neurocirugía del Hospital Provincial Docente "Saturnino Lora" de Santiago de Cuba, durante el período comprendido desde enero del 2008 a diciembre del 2013.
Resultados: En los casos estudiados (n= 31) la edad tuvo un recorrido entre 19 y 76 años, predominó el sexo femenino (54,8 %), las lesiones benignas (64,5 %), así como mayor localización dorsal y extradural en el eje espinal.
Conclusiones: Las principales características clínicas y epidemiológicas fueron: edad de presentación más frecuente en la sexta década de la vida, sintomatología con compromiso neurológico variable, dolor del raquis en todos los casos y predominio de lesiones benignas.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Sharma M, Sonig A, Ambekar S, Nanda A. Discharge dispositions, complications, and costs of hospitalization in spinal cord tumor surgery: analysis of data from the United States Nationwide Inpatient Sample, 2003-2010. J Neurosurg Spine. 2014;20:125-141.

  2. Karhade AV, Vasudeva VS, Dasenbrock HH, Lu Y, Gormley WB, Groff MW. Thirty-day readmission and reoperation after surgery for spinal tumors: a National Surgical Quality Improvement Program analysis. Neurosurg Focus. 2016;41(13):[aprox. 20 pant.]. Access: 03/03/2018. Available from: http://thejns.org/doi/full/10.3171/2016.5.FOCUS16168

  3. Greenberg MS. Manual de Neurocirugía. 2da edición. Buenos Aires: Ediciones Journal; 2013.

  4. Bansal S, Ailawadhi P, Suri A, Kale SS, Sarat Chandra P, Singh M. Ten years' experience in the management of spinal intramedullary tumors in a single institution. J Clin Neurosci. 2013;20(2):292-8. Access: 03/03/2018. Available from: https://www.jocn-journal.com/article/S0967-5868(12)00351-7/fulltext

  5. Pendleton C, Rincon-Torroella J, Gokaslan ZL, Jallo GI, Quinones-Hinojosa A. Challenges in early operative approaches to intramedullary spinal cord tumors: Harvey Cushing's perspective. J Neurosurg Spine. 2015;23:412-8. Access: 3/03/2018. Available from: http://thejns.org/doi/full/10.3171/2014.12.SPINE13427

  6. Ogden AT, Schwartz TH, McCormick PC. Spinal Cord Tumors in Adults. En: Winn HR, editor. Youmans Neurological Surgery. Philadelphia: Elsevier;2011. p. 3131-43.

  7. Karsy M, Guan J, Sivakumar W, Neil JA, Schmidt MH, Mahan MA. The genetic basis of intradural spinal tumors and its impact on clinical treatment. Neurosurg Focus. 2015;39(13):[aprox. 31 pant.]. Access: 03/03/2018. Available from: http://thejns.org/doi/full/10.3171/2015.5.FOCUS15143

  8. Ottenhausen M, Ntoulias G, Bodhinayake I, Rupert FH, Schreiber S, Förschler A. Intradural spinal tumors in adults-update on management and outcome. Neurosurg Rev, 2018;41(1):1-18. Access: 03/03/2018. Available from: https://doi.org/10.1007/s10143-018-0957-x

  9. Hirano K, Imagama S, Sato K, Kato F, Kawa Y, Yoshihara H. Primary spinal cord tumors: review of 678 surgically treated patients in Japan. A multicenter study Eur Spine J. 2012;21(10):2019-26.

  10. Hernández Solarte A, Losada Díaz A, Ortega Campos LG. Estudio de la incidencia de tumores raquimedulares tratados en el servicio de neurocirugía hospital San Juan de Dios y revisión del tema. Neuroeje. 1999;13(3): 102-8. Acceso: 03/03/2018. Disponible en: http://www.binasss.sa.cr/revistas/neuroeje/v13n3/art7.pdf

  11. Da Roza P. Primary intraspinal tumours: their clinical presentation and diagnosis. An analysis of ninety-five cases. J Bone Joint Surg Am. 2009;46:8-15.

  12. Matsumoto M, Tsuji T, Iwanami A, Watanabe K, Hosogane N, Ishii K. Total in bloc spondylectomy for spinal metastasis of differentiated thyroid cancers: a long-term follow-up. Spinal Disord Tech. 2013;26(4): 137-42. Access: 3/03/2018] Available from: https://insights.ovid.com/crossref?an=00024720-201306000-00013#

  13. Kaloostian PE, Zadnik PL, Etame AB, Vrionis FD, Gokaslan ZL, Sciubba DM. Surgical management of primary and metastatic spinal tumors. Cancer Contr. 2014;21:133-9.

  14. Mesfin A, Buchowski JM, Gokaslan ZL, Bird JE. Management of metastatic cervical spine tumors. J Am Acad Orthop Surg. 2015;23:38-46.

  15. Schairer WW, Carrer A, Sing DC, Chou D, Mummaneni PV, Hu SS. Hospital readmission rates after surgical treatment of primary and metastatic tumors of the spine. Spine 2014;39(21):1801-8. Access: 03/03/2018. Available from: https://journals.lww.com/spinejournal/Fulltext/2014/10010/Hospital_Readmission_Rates_After_Surgical.17.aspx

  16. Zwagerman NT, McDowell MM, Hamilton RL, Monaco III EA, MD, Flickinger JC, Gerszten PC. Histopathological examination of spine tumors after treatment with radiosurgery. Neurosurg Focus. 2016;41(2):1-4. Access: 03/03/2018. Available from: http://thejns.org/doi/full/10.3171/2016.5.FOCUS16119

  17. Loya JJ, Jung H, Temmins C, Cho N, Singh H. Primary spinal germ cell tumors: a case analysis and review of treatment paradigms. Case Rep Med. 2013(2013):[aprox. 16 scr ]. Access: 03/03/2018. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838823/

  18. Molina CA, Sciubba DM. Tumors of the Spine. En: Baaj AA, Mummaneni PV, Uribe JS, Vaccaro AR, Greenberg MS. Handbook of Spine Surgery. New York: Thieme Medical Publishers, Inc; 2012.

  19. Alpízar-Aguirre A, Chávez C, Zarate B, Rosales LM, Baena L, Reyes A. Tumores intradurales extramedulares primarios tratados en el instituto nacional de rehabilitación. Cir Ciruj. 2009;77:107-10. Acceso: 03/03/2018. Disponible en: http://www.medigraphic.com/pdfs/circir/cc-2009/cc092e.pdf

  20. Claus E, Abdel-Wahab M, Burger PC, Engelhard H. Defining future directions in spinal cord tumor research: J Neurosurg Spine. 2010;12(2):117-21. Access: 03/03/2018. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193276/pdf/nihms-278450.pdf

  21. Tobin MK, Geraghty JR, Engelhard HH, Linninger AA, Mehta AI. Intramedullary spinal cord tumors: a review of current and future treatment strategies. Neurosurg Focus. 2015;39(10):[aprox. 25 scr.]. Access: 03/03/2018. Available from: http://thejns.org/doi/full/10.3171/2015.5.FOCUS15158

  22. Mc Cormick P. Intradural extramedullary tumors. En: Quiñones-Hinojosa A. Operative Neurosurgical Techniques Indications, Methods, And Results. Philadelphia: Elsevier; 2012. p. 2126-2133.

  23. Ostrom QT, Gittleman H, Liao P, Rouse C, Chen Y, Dowling J. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. Neuro Oncol. 2014;16(Suppl 4):1-63.

  24. Samuel N, Tetreault L, Santaguida C, Nater A, Moayeri N, Massicotte EM. Clinical and pathological outcomes after resection of intramedullary spinal cord tumors: a single-institution case series. Neurosurg Focus. 2016;41(2):1-8. Access: 03/03/2018. Available from: https://thejns.org/downloadpdf/journals/neurosurg-focus/41/2/article-pE8.pdf

  25. Bakar D, Tanenbaum JE, Phan K, Alentado VJ, Steinmetz MP, Benzel EC. Decompression surgery for spinal metastases: a systematic review. Neurosurg Focus. 2016;41(2):1-35. Access: 03/03/2018. Available from: https://thejns.org/downloadpdf/journals/neurosurg-focus/41/2/article-pE2.pdf

  26. He J, Xiao J, Peng X, Duan B, Li Y, Ai P. Dose escalation by image-guided intensity-modulated radiotherapy leads to an increase in pain relief for spinal metastases: a comparison study with a regimen of 30 Gy in 10 fractions. Oncotarget, 2017;8(68):112330-40. Access: 03/03/ 2018. Available from: http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=18979&path[]=60831

  27. Sung WS, Sung MJ, Chan JH, Manion B, Song J, Dubey A. Intramedullary spinal cord metastases: a 20-year institutional experience with a comprehensive literature review. World Neurosurg. 2013;79:576-84.

  28. Sun J, Wang Z, Li Z, Liu B. Microsurgical treatment and functional outcomes of multi-segment intramedullary spinal cord tumors. Clin Neurosci. 2009;16(5):666-71. Access: 03/03/2018. Available from: https://www.sciencedirect.com/science/article/pii/S0967586808004803?via%3Dihub

  29. Guerrero-Suárez PD, Magdaleno-Estrella E, Guerrero-López P, Vargas-Figueroa AI, Martínez-Anda JJ. Intradural spinal tumors: 10 - years surgical experience in a single institution. Clin Neurol Neurosurg. 2018;169:98-102.




2020     |     www.medigraphic.com