2018, Number 3
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Rev Cubana Invest Bioméd 2018; 37 (3)
Fluctuations of zinc homeostatics related to the human growthdevelopment stages
Ramírez EOE, Ley LLR, Reyes MR, Bastart OE, Ramis BJA
Language: Spanish
References: 60
Page: 1-16
PDF size: 161.93 Kb.
ABSTRACT
It is known that the Factor of Insulin Dependent Growth I (IGF-I), it diminishes their
expression in presence of plasmatic deficit of zinc. The objective of the present
revision is to relate fluctuations of the homeostasis of the zinc with stages of the
human growth-development. Of the discussion of it dates it presented one has that:
the human growth-development is a process with incidences of the calcium and of the
zinc, where the deficit of zinc is a factor of high risk for the premature birth of infants
and of children with drop carves; enough evidences exist to infer a direct weak
association between the gradual increment of the plasmatic levels of zinc and calcium
with the increase of the age during the childhood and the adolescence and that the
interaction of collaboration between the calcium and the zinc in the osteogenesis,
suffers a differentiation of functions in the enchondral ossification , and it becomes a
competition relationship in the formation of the dental enamel ; it is manifested as
tendency an increment of the plasmatic zinc with the increase of the age, with due
biases to the overweight and the obesity and to the woman's productive fertility. Then
it can be considered finally that the homeostasis of the plasmatic zinc, stabilized in an
interval of normal values for a given stadium, favorable the necessary and enough
growth-development being the aging an involution moment in that tendency of
increment of plasmatic values of zinc with the age.
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