2019, Number 4
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Rev Med MD 2019; 10.11 (4)
Time of healing and impact on fecal continence according to the Wexner scale between fistulotomy and fistulectomy for the management of perianal fistulas
Beltrán-Ríos D, Latorraca-Santamaría JI, González-Duarte JA, Betancourt-Vicencio S, Esparza-González A, Delgado-Garay FG, Álvarez-Zavala M, Enciso-Pérez D, Magaña-Vaca JF, Hernández- Gómez F, Zepeda-Solís C, Navarro-Lara E
Language: Spanish
References: 42
Page: 259-264
PDF size: 544.12 Kb.
ABSTRACT
Introduction.
The management of anal fistulas represents a challenge for the surgeon due to the heterogeneity of the condition and the potential adverse
events on the anal continence of surgical treatment. Fistulotomy and fistulectomy are the two main surgical techniques used in this entity.
Because the information on these surgical techniques is varied by the design of the studies and the heterogeneity of the populations studied, the
objective of this study was to describe and compare the impact on anal continence according to the Wexner scale and epithelialization time of the
surgical wound in Mexican population in a reference hospital.
Methods.
It was a retrospective analytical study in which all individuals with a diagnosis of perianal fistula were included who were treated in the
coloproctology service of the Hospital Civil de Guadalajara Fray Antonio Alcalde during the period from January 2016 to November 2018 The
clinical, demographic characteristics, the type of procedure used (fistulotomy or Fistulectomy), the healing time and the Wexner scale scores
before and after surgery were analyzed. Descriptive statistics were used. Categorical variables were compared with
χ
2 test or Fisher’s exact test;
the continuous variables using Student’s t or U of Mann-Whitney, according to their distribution. For multiple continuous variables, they were
compared with ANOVA or Kruskal Wallis. To investigate the association of the variables with incontinence, a univariate and multivariate
analysis was performed using logistic regression, taking for the multivariate analysis the variables that had a value of p ‹0.2 in the univariate
analysis. Multiple regression was performed to investigate the association of variables with healing time. A value of p ‹0.05 was determined
statistically significant.
Results.
Of the 140 patients were analyzed. 88 of them (63%) had fistulectomy. The majority were men of the fifth decade of life. There was no
difference in terms of evolution time; history of previous anorectal surgery; comorbidities nor in the complexity of the fistulas between both
groups. In the fistulectomy group, a greater number of plasties were performed, they had a higher proportion of incontinence and more time for
healing. While in the fistulotomy group, more post-surgical complications were reported, where the surgical wound hematoma was the most
frequent. 21 individuals (15%) presented some degree of continence alteration according to the Wexner scale. The variables associated with the
development of incontinence were the history of fistulectomy and the classification of the fistula according to the Parks classification.
Discussion.
In our center, fistulectomy has a longer time for scarring and a greater proportion of incontinence compared to fistulotomy. However, the first
was performed in a greater proportion for the treatment of complex fistulas. This first report provides valuable information about our hospital
experience and provides the opportunity to conduct prospective comparative studies between these two techniques.
REFERENCES
Deeba S, Aziz O, Sains PS, Darzi A. Fistula-in-ano: advances in treatment. Am J Surg. 2008;196(1):95-99.
Joseph C. Carmichael and Steven Mills. The ASCRS Textbook of Colon and Rectal Surgery. In: Scott R. Steele, MD. Tracy L. Hull, MD. Thomas E. Read, MD. Theodore J. Saclarides, MD. Anthony J. Senagore, MD. Charles B. Whitlow M, ed. The ASCRS Textbook of Colon and Rectal Surgery. 3rd ed. Arlington Heights, Il, USA: Spinger; 2016:3-26.
Madoff RD, Parker SC, Varma MG, Lowry AC. Faecal incontinence in adults. 2004;364:621-632.
Canal A. Anorectal anatomy and physiology. 2001;30(1):1-13.
Smith LE, Jorge JMN, Wexner SD. Etiology and Management of Fecal Incontinence. :77-97.
Shafik A. A Concept of the Anatomy of the Anal Sphincter Mechanism and the Physiology of Defecation. 1987:970-982.
Lestar B, Penninckx F, Kerremans R. The composition of anal basal pressure. Color Dis. 1989;4:118-122.
Blumetti J, Abcarian A, Quinteros F, Chaudhry V, Prasad L, Abcarian H. Evolution of Treatment of Fistula in Ano. 2012:1162-1167. doi:10.1007/s00268-012-1480-9.
Murtaza G, Shaikh FA, Chawla T, Rajput BU, Shahzad N, Ansari S. Fistulotomy versus fistulectomy for simple fistula in ano: A retrospective cohort study. J Pak Med Assoc. 2017;67(3):339-342.
Hirschburger M, Schwandner T. Fistulectomy with primary sphincter reconstruction in the treatment of high transsphincteric anal fistulas. 2014:247-252. doi:10.1007/s00384-013-1788-4.
Whiteford MH, Kilkenny J, Hyman N, et al. Practice parameters for the treatment of perianal abscess and fistula-in-ano (revised). Dis Colon Rectum. 2005;48(7):1337-1342.
Cariati A. Fistulotomy or seton in anal fistula: A decisional algorithm. Updates Surg. 2013;65(3):201- 205.
Garg P. Is fistulotomy still the gold standard in present era and is it highly underutilized?: An audit of 675 operated cases. Int J Surg. 2018;56(May):26- 30.
Garg P. Comparing existing classifications of fistula-in-ano in 440 operated patients: Is it time for a new classification? A Retrospective Cohort Study. Int J Surg. 2017;42:34-40.
Pastor C, Hwang J, Garcia-aguilar J. Reprint to: Fistulo tomy. Semin Colon Rectal Surg. 2018;000(2009):1-5.
Tasci I, Erturk S, Alver O. Coring-out fistulectomy with a newly designed “fistulectome” for complicated perianal fistulae: A retrospective clinical analysis. Color Dis. 2013;15(7):396-401.
Göttgens KWA, Janssen PTJ, Heemskerk J, et al. Long-term outcome of low perianal fistulas treated by fistulotomy: a multicenter study. Int J Colorectal Dis. 2014;30(2):213-219.
Toyonaga T, Matsushima M. Factors affecting continence after fistulotomy for intersphincteric fistula-in-ano.2007:1071-1075. doi:10.1007/s00384-007-0277-z.
Arroyo A, Pérez-Legaz J, Moya P, et al. Fistulotomy and sphincter reconstruction in the treatment of complex fistula-in-ano: Long-term clinical and manometric results. Ann Surg. 2012;255(5):935-939.
Xu Y, Liang S, Tang W. Meta-analysis of randomized clinical trials comparing fistulectomy versus fistulotomy for low anal fistula. Springerplus. 2016;5(1). doi:10.1186/s40064-016-3406-8.
Mascagni D, Mascagni P, Toscana E, et al. Total Fistulectomy, Anoplasty, Sphincteroplasty and Partial Closure of Residual Cavity for Trans- Sphincteric Perianal Fistula. Gastroenterology. 2017;152(5):S1259.
Limongelli P, Brusciano L, del Genio G, et al. Marsupialization compared to open wound improves dressing change and wound carem anagementafter fistl ec tomy forlow transsphincteric anal fistula. Int J Colorectal Dis. 2016;31(5):1081-1082.
Malouf AJ, Buchanan GN, Carapeti EA, et al. A prospective audit of fistula-in-ano at St. Mark's hospital. Color Dis. 2002;4(1):13-19.
Gupta PJ. Radiofrequency fistulotomy: A better alternative for treating low anal fistula. Sao Paulo Med J. 2004;122(4):172-174.
Rizzo JA, Naig AL. Anorectal abscess and Fistulain- Ano: Evidence-Based Management. Surg Clin North Am. 2010;90:45-68.
Liu WY, Aboulian A, Kaji AH, Kumar RR. Longterm results of ligation of intersphincteric fistula tract (LIFT) for fistula-in-ano. Dis Colon Rectum. 2013;56(3):343-347.
Chalya PL, Mabula JB. Fistulectomy versus fistulotomy with marsupialisation in the treatment of low fistula-in-ano: A prospective randomized controlled trial. Tanzan J Health Res. 2013;15(3):1-9.
Litta CRF, Parello LDA. Fistulotomy or fistulectomy and primary sphincteroplasty for anal fistula ( FIPS ): a systematic review. Tech Coloproctol. 2015;19(7):391-400.
Ganesan R, Karunakaran K, Anandan H. A comparative study between fistulotomy and fistulectomy in management of low anal fistulae. 2017;4(11):3665-3669.
Kronborg O. To lay open or excise a fistula-in- ano: a randomized trial. Br J Surg. 1985;72(July):1209701.
Steele SR, Rafferty MDJF. The American Society of Colon and Rectal Surgeons' Clinical Practice Guideline for the Treatment of Fecal Incontinence. 2015:623-636.di:10.1097/DCR.0000000000000397.
Jorgensen SN, Sanders JR. Mathematical models of wound healing and closure : a comprehensive review. Med Biol Eng Comput. 2016;54:1297-1316. doi:10.1007/s11517-015-1435- z.
Lorenz HP, Longaker MT. Wounds : Biology , Pathology , and Management. In: Li M, ed. Essential Practice of Surgery. 2nd ed. New York: Springer; 2003:77-88.
Issue FT. Updates in wound healing : Mechanisms and translation. Exp Dermatol. 2017;26:97-98. doi:10.1111/exd.13281.
Buchanan GN, Carapeti EA, et al. Characteristicas of fistula-in-ano at St. Mark's hospital. Color Dis. 2015;9(5):13-19.
Sahnan K, Askari A, Adegbola SO, et al. Natural history of anorectal sepsis. Br J Surg. 2017;104(13):1857-1865. doi:10.1002/bjs.10614.
Ramanujam PS, Prasad ML, Abcarian H, Tan AB. Perianal abscesses and fistulas - A study of 1023 patients. Dis Colon Rectum. 1984;27(9):593- 597. doi:10.1007/BF02553848.
Hämäläinen KP, Sainio AP. Incidence of fistulas after drainage of acute anorectal abscesses. Dis Colon Rectum. 1998;41(11):1357-61; discussion 1361-2. doi:10.1016/j.jcis.2015.12.024.
Hamadani A, Haigh PI, Liu ILA, Abbas MA. Who is at risk for developing chronic anal fistula or recurrent anal sepsis after initial perianal abscess? Dis Colon Rectum. 2009;52(2):217-221. doi:10.1007/DCR.0b013e31819a5c52.
Nordgren S, Fasth S. Colorectal Disease Incidence and outcome of surgical treatment. 1992:214-218.
Vasilevsky CA, Gordon PH. Results of treatment of fistula-in-ano. Dis Colon Rectum. 1985;28(4):225-231. doi:10.1007/BF02554037.
Toyonaga T, Matsushima M, Tanaka Y, et al. Non-sphincter splitting fistulectomy vs conventional fistulotomy for high trans-sphincteric fistula-in-ano: A prospective functional and manometrics tudy. Int JColorectal Dis, 2007;22(9):1097-1102. doi:10.1007/s00384-007- 0288-9.