Arbovirus Causing Hemorrhagic Fever at IMSS

Joel Navarrete-Espinosa; Héctor Gómez-Dantés

2006, Number 4

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Rev Med Inst Mex Seguro Soc 2006; 44 (4)

Arbovirus Causing Hemorrhagic Fever at IMSS

Navarrete-Espinosa J, Gómez-Dantés H

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Language: Spanish
References: 25
Page: 347-353
PDF size: 120.37 Kb.

ABSTRACT

Objective: To know the arbovirus causing hem-orrhagic fever in patients at the Mexican Institute of Social Security.
Material and methods: a follow-up study was made in patients with probable diagnosis of hemorrhagic dengue. Blood samples were taken to look for dengue fever, yellow fever and San Luis, Tonate and Mayaro encephalitis viruses. Frequencies and proportions of the interest variables were analyzed.
Results: 35 patients were studied. Isolation and PCR results of the 13 samples were negative in 12 of them and positive to denguevirus-3 in one of them. The determination of IgM was positive for dengue fever in 25 cases; 2 were positive to Mayaro virus and 8 were negative to what was looked for. Hemorrhages and thrombocytopenia were more frequent in patients infected with dengue and Mayaro viruses; jaundice and encephalopathy were more frequent in the latter, and renal dysfunction, in patients with a negative result. Evolution was satisfactory in all cases, except for one (Mayaro), which presented hemorrhages, thrombocytopenia, jaundice and encephalopathy that lead to death.
Conclusions: the results show the risk of appearance and dissemination of several vector- born diseases in Mexico. Thus, they require intensive epidemiological surveillance to identify them and to know their real occurrence and specific clinical profile.

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