2018, Number 6
Hypertriglyceridemic waist phenotype and its association with cardiovascular risk factors
Language: Spanish
References: 30
Page: 949-964
PDF size: 924.63 Kb.
ABSTRACT
Introduction: The hypertriglyceridemic waist phenotype is related to the presence of hyperinsulinemia, hypertriglyceridemia, and hypercholesterolemia and consequently, it is a risk of cardiovascular diseases and type 2 diabetes mellitus.Objective: To determine the association of hypertriglyceridemic waist phenotype with the main cardiovascular risk factors.
Material and Methods: A descriptive study was carried out with a probabilistic sample obtained from a multi-stage method. The sample consisted of 1108 subjects between 15 and 74 years old, included in the surveillance component for noncommunicable diseases (NCDs) from the CARMEN initiative in Cienfuegos. The variables evaluated were: sex, skin color, smoking, hypertension, obesity, physical activity, diabetes mellitus, body mass index, abdominal circumference, total cholesterol, and triglycerides. The Prevalence Ratio (PR) was determined for the different variables. The level of significance required was 95%. The research was approved by the Scientific Council of the University of Medical Sciences of Cienfuegos and the Research Ethics Committee. The results are presented in tables and figures.
Results: PR showed a greater risk of presenting the phenotype in females (2,31), as well as in subjects over 45 years (2,92), obese (19,24), and hypertensive and diabetics for a PR of (2.96 and 2.30), respectively.
Conclusions: There is a significant relationship between hypertriglyceridemic waist phenotype and the main cardiovascular risk factors such as increasing age, atherogenic index, cholesterol levels, diabetes mellitus, and hypertension.
REFERENCES
GBD 2013 Mortality and Causes of Death Collaborators. Global, regional, and national agesex specific all-cause and cause-specific mortality for 240 causes of death, 1990‒2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet [Internet]. 2015 Jan [cited 30/08/2018]; 385(9963):117-171. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PM C4340604/
Wei C L, Chu Chang K, Chiou ST, Chan Chuan C, Chen CL, Lai MS et al. Adult mortality of diseases and injuries attributable to selected metabolic, lifestyle, environmental, and infectious risk factors in Taiwan: a comparative risk assessment. Popul Health Metr[ Internet]. 2017 [cited 30/08/2018]; 15(1):17. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PM C5415794/
Diéguez-Martínez M, Miguel-Soca P, Rodríguez-Hernández R, López-Báster J, Poncede- León D, Reyna-Carralero J. Prevalencia de hipertrigliceridemia y factores de riesgo cardiovascular en estudiantes de la Universidad de Ciencias Médicas. Holguín, 2014-2015. Medisur [Internet]. 2018 [citado 30/08/2018]; 16(1):[aprox. 11p.]. Disponible en: http://medisur.sld.cu/index.php/medisur/article /view/3626/2510
Delgado-Acosta H, Lastre-Navarro K, Valdés- Gómez M, Benet-Rodríguez M, Morejón- Giraldoni A, Zerquera-Rodríguez J. Prevalencia de hipertensión arterial en el Área I del municipio Cienfuegos. Segunda medición de la iniciativa CARMEN. Rev Finlay [Internet]. 2015 [citado 30/08/2018]; 5(1):[aprox. 7p.]. Disponible en: http://www.revfinlay.sld.cu/index.php/finlay/art icle/view/322
Zhao K, Yang SS, Wang HB, Chen K, Lu ZH, Mu YM. Association between the Hypertriglyceridemic Waist Phenotype and Prediabetes in Chinese Adults Aged 40 Years and Older. J Diabetes Res [Internet]. 2018 Jun 25 [cited 30/08/2018]; 2018: [aprox. 22 p.]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PM C6036789/
Morejón A, Rivas E, Salas V, Benet M. Prevalencia del fenotipo hipertrigliceridemia cintura abdominal alterada: resultados de la segunda medición de la iniciativa CARMEN. Rev Finlay [Internet]. 2014 [citado 13/04/2018]; 4(4): [aprox. 8 p.]. Disponible en: http://www.revfinlay.sld.cu/index.php/finlay/art icle/view/321/1359
Silva LC, Benet M, Morejón A, Ordúñez P. An efficient sampling approach to surveillance of non-communicable disease risk factors in Cienfuegos, Cuba. Rev MEDICC [Internet]. 2012 Oct [cited 13/04/2018]; 14(4):[aprox. 6 p.]. Disponible en: http://www.medigraphic.com/pdfs/medicrevie w/mrw-2012/mrw124h.pdf
Freitas R, Fonseca MJ, Schmidt MI, Molina MC, Almeida MC. Fenótipo cintura hipertrigliceridêmica: fatores asociados e comparação com outros indicadores de risco cardiovascular e metabólico no ELSA-Brasil. Cad Saúde Pública[Internet]. [cited 30/08/2018]; 34(4):[aprox. 32p.]. Disponible en: http://www.scielo.br/pdf/csp/v34n4/1678- 4464-csp-34-04-e00067617.pdf
Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, et al; National Heart, Lung and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA. 2003 May 21;289(19):2560-72.
Rivas-Alpizar E, Zerquera-Trujillo G, Hernández-Gutiérrez C, Vicente-Sánchez B. Manejo práctico del paciente con diabetes mellitus en la Atención Primaria de Salud. Rev Finlay [Internet]. 2011[citado 29/09/2018]; 1(3): [aprox. 22 p.]. Disponible en: http://www.revfinlay.sld.cu/index.php/finlay/art icle/view/69/1232
Gómez LF, Duperly J, Lucumí DI, Gámez R, Venegas AS. Nivel de actividad física global en la población adulta de Bogotá (Colombia): Prevalencia y factores asociados. Gac Sanit [Internet]. 2005 Jun [cited 30/09/2018]; 19(3): [aprox. 14 p.]. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttex t&pid=S0213-91112005000300005&lng=es
León-Regal M, Álvarez-Hernández R, Benet- Rodríguez M, Morales-Pérez C, Yanes-Seijo R, de- Armas-García J. Reactividad cardiovascular: su asociación con la actividad física, y algunas variables hemodinámicas y antropométricas. Rev Finlay [Internet]. 2016 [citado 30/08/2018]; 6(3): [aprox. 13 p.]. Disponible en: http://www.revfinlay.sld.cu/index.php/finlay/art icle/view/432
van Deventer Hendrick E, Miller W. Greg, Myers Gary L, SakurabayashiIkunosuke, Bachmann Lorin M, Caudill Samuel P, et al. El Colesterol no-HDL demuestra una mejor exactitud en el score de la clasificación del riesgo cardiovascular comparado con el colesterol LDL, directo o calculado, en una población dislipémica. Acta Bioquím Clín Latinoam [Internet]. 2011 Dic [citado 30/08/2018]; 45(4): [aprox. 22 p.]. Disponible en: http://www.scielo.org.ar/- scielo.php?script=sci_arttext&pid=S0325-2- 9572011000400009&lng=rd
Calcaterra V, De Giuseppe R, Biino G, Mantelli M, Marchini S, Bendotti G, et al. Relation between circulating oxidized-LDL and metabolic syndrome in children with obesity: the role of hypertriglyceridemic waist phenotype. J Pediatr Endocrinol Metab [Internet]. 2017 [cited 30/08/2018]; 30(12): [aprox. 12 p.]. Available from: https://www.degruyter.com/view/j/jpem.2017. 30.issue-12/jpem-2017-0239/jpem-2017- 0239.xml
Antoniolli LP, Nedel BL, Pazinato TC, de Andrade Mesquita L, Gerchman F. Accuracy of insulin resistance indices for metabolic syndrome: a cross-sectional study in adults. Diabetol Metab Synd [Internet]. 2018 [cited 30/08/2018]; 10(65): [aprox. 22 p.]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PM C6102896/
Gasevic D, Carlsson AC, Lesser IA, Mancini GJ, Lear SA. The association between “hypertriglyceridemic waist” and sub-clinical atherosclerosis in a multiethnic population: a cross-sectional study. Lipids Health Disease [Internet]. 2014[cited 30/08/2018]; 13(1):38. Available from: https://lipidworld.biomedcentral.com/articles/1 0.1186/1476-511X-13-38
Zainuddin LR, Isa N, Muda WM, Mohamed HJ. The prevalence of metabolic syndrome according to various definitions and hypertriglyceridemicwaist in malaysian adults. Int J Prev Med [Internet]. 2011 [cited 30/08/2018]; 2(4): 299- 237]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PM C3237265/
Amini M, Esmaillzadeh A, Sadeghi M, Mehvarifar N, Amini M, Zare M. The association of hypertriglyceridemic waist phenotype with type 2 diabetes mellitus among individuals with first relative history of diabetes. J Res Med Sci [Internet]. 2011[cited 30/08/2018]; 16(2):156- 164]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc 3214297/
Freitas RS, Fonseca MJ, Schmidt MI, Molina CB, Almeida CC. Fenótipo cintura hipertrigliceridêmica: fatores associados e comparação com outros indicadores de risco cardiovascular e metabólico no ELSA-Brasil. Cad Saúde Pública [Internet]. 2018 Mar 29[cited 30/08/2018]; 34(4): [aprox. 26 p.]. Available from: http://www.scielo.br/scielo.php?script=sci_artte xt&pid=S0102- 311X2018000405002&lng=en&nrm=iso&tlng=en
Celis-Morales C, Salas C, Álvarez C, Aguilar Farías N, Ramírez Campillos R, Leppe J, et al. Un mayor nivel de actividad física se asocia a una menor prevalencia de factores de riesgo cardiovascular en Chile: resultados de la Encuesta Nacional de Salud 2009-2010. Rev Méd Chile [Internet]. 2015 Nov [ citado 12/04/2018];143(11):[aprox. 16 p.]. Disponible en: https://scielo.conicyt.cl/scielo.php?script=sci_ar ttext&pid=S0034-98872015001100009&lng=es