2006, Number 1
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Med Sur 2006; 13 (1)
Autoimmune hypophysitis
Arias SEA, Gómez MO, Gutiérrez DLG, Vidal-Tamayo R
Language: Spanish
References: 12
Page: 3-6
PDF size: 38.51 Kb.
ABSTRACT
Autoimmune hypophysitis is a rare disease, but is the most common form of chronic inflammation that affects the pituitary gland. The first description of this disease was made in 1962 by Goudie and Pinkerton. Nowadays there are 3 morphologic forms of autoimmune hypophysitis: lymphocytic adenohypophysitis (LAH), lymphocytic infundibulohypophysitis (LINH) and lymphocytic panhypophysitis (LPH). This disease shows an important correlation with pregnancy. The clinical manifestations are divided in symptoms that arise from selar compression such as cephalea or visual alterations and symptoms related to hormonal alterations such as ACTH, TSH, gonadotropines and prolactin deficiencies. Treatment of these patients consists in controlling symptoms by reduction of the pituitary mass by means of surgery or lympholitic drugs.
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