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2018, Number 3

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Anales de Radiología México 2018; 17 (3)

Paget’s disease, a special form of breast cancer: clinical, image and pathological findings. Review of six cases

Dávila-Zablah YJ, Garza-Montemayor ML

Language: Spanish
References: 19
Page: 216-225
PDF size: 543.01 Kb.


ABSTRACT

Objective: To report the frequency of Paget’s disease in Breast Center of San José TecSalud Hospital, Monterrey, analysis and comparison with the literature of its clinical characteristics and by image.
Method: Cross-sectional, retrospective study. A review of the positive results for cancer by pathological anatomy from 2008 to 2016 of the patients biopsied in our institution and of the confirmed cases of Paget’s disease, their clinical and imaging findings were analyzed. Our results were compared with that reported in the literature.
Results: The prevalence of Paget’s disease was 0.85% of all breast carcinomas in our institution, all of the patients female. The age range was from 25 to 86 years, with an average of 50 years. The majority of our patient’s present clinical changes in the nipple-areola complex and only one presents palpable mass. 100% of our cases were associated with cancer. The most frequent mammography findings in our study were calcifications, nipple retraction and nipple. Mammography was negative by 16%. Ultrasound did not improve the detection of cancer in the present study; its main contribution was the detection of metastatic lymph nodes. In one patient with negative mammography and ultrasound, a resonance lesion was demonstrated.
Conclusion: Paget’s disease is an infrequent disease; however, it is very important for the radiologist to know this pathology and its differential diagnosis due to its high association with carcinoma and thus help in its early diagnosis and adequate treatment.


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