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ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC

2019, Number 1

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An Med Asoc Med Hosp ABC 2019; 64 (1)

Characterization of the high-sensitivity troponin I curve after a percutaneous coronary intervention

López MJG, Cabrera LCF, Ibarra TAD, Heredia SAC, Ávila VJA, López CJ, Soto LME

Language: Spanish
References: 26
Page: 6-11
PDF size: 207.64 Kb.


ABSTRACT

Introduction: The cardiac troponins I and T are highly specific myocardial markers; current assays called high-sensitivity troponins detect concentrations ‹ 1 ng/L (picograms). During coronary instrumentation, an increment of troponins occurs, ranging from ‹ 10% to 50%; however, the clinical usefulness of this assumed myocardial damage is in debate. Objective: To characterize the high-sensitivity troponin I curve after coronarography with or without angioplasty. Material and methods: This was an analytic, retrospective study. We considered all the coronary procedures performed during a three-year period in the ABC Medical Center Campus Observatorio and Campus Santa Fe; 199 cases were deemed to analysis, 93 (47%) for high-sensitivity troponin I and 106 (53%) for conventional troponin I. Results: The highest concentrations were observed in the 24 hour-measurements, as expected; the subsequent measurements for 48 and 72 hours were non-exclusive among them and showed a broad range of values; the discrimination was poorer for the conventional troponin I. The anterior descending artery was the most frequently treated artery (in 35%) and caused the highest concentration in the first 24-hour measurement, followed by the right coronary artery. The femoral approach caused slightly less high sensitive troponin I release in comparison to the radial access. The conventional troponin I followed a different pattern; the peak of the curve was secondary to the instrumentation of two simultaneous vessels that did not include the anterior descending artery. Conclusion: We characterized the high sensitive troponin I curve and established a security range in percentiles for patients post-angioplasty, mainly for those with ST segment elevation acute myocardial infarction.


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