Benítez RFE

Language: Spanish
References: 36
Page: 111-119
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ABSTRACT

The stem cells are cells of variable cellular potency with self-renewal capacity, which participate in the tissue formation, maintenance and repair during embryonic development and adult life. The cellular commitment that the stem cells adopt towards a specific cellular fate is the product of the narrow line between the components of the stem cell and its niche. Throughout the process of cellular commitment, the stem cell organelles undergo structural, functional and metabolic changes. This review focuses on the organellar modifications, in the nucleus, cytoskeleton and mitochondria that occurs when the cellular potency of embryonic stem cells (ESC) changes to be conserved or differentiated towards a specific cell type.

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