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2018, Número 4

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Rev Educ Bioquimica 2018; 37 (4)


Dinámica organelar y funcional de las células troncales

Benítez RFE

Idioma: Español
Referencias bibliográficas: 36
Paginas: 111-119
Archivo PDF: 731.44 Kb.


RESUMEN

Las células troncales son células de potencia celular variable con capacidad de autorrenovación, que participan en la formación, mantenimiento y restauración tisular durante el desarrollo embrionario y la vida adulta. El compromiso que adoptan las células troncales hacia un destino celular específico es producto de la estrecha coordinación entre los componentes de célula troncal y su nicho. A lo largo del proceso de compromiso celular, los organelos de la célula troncal se someten a cambios estructurales, funcionales y metabólicos. Esta revisión contrasta las modificaciones organelares, en el núcleo, citoesqueleto y mitocondria, que se presentan cuando la potencia celular de las células troncales embrionarias (ESCs) cambia al conservarse o diferenciarse hacia un tipo celular específico.


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