Nardelli AR, Marcarini R, Alarcon NA, Alves PAD

Language: English
References: 15
Page: 209-212
PDF size: 279.80 Kb.

ABSTRACT

The plantar fibromatosis (PF), also known as Ledderhose’s disease, is characterized by affecting the plantar aponeurosis. In a general way, it is a benign fibrous condition still quite unclear in its various aspects, such as its etiology and treatment. To date, it has not been described in association with AIDS. Our patient presented PF previously hospitalization due to occurrence of many opportunistic infections due to AIDS at an advanced stage. We have described the case of a 45 year-old male patient with acquired immunodeficiency syndrome at a late stage, associated with Dupuytren’s disease (DD) and the emergence of bilateral PF. Treatment was conservative as the plantar lesions were asymptomatic and the risk of recurrence with invasive measures is high. About 15% of people affected with PF have concomitant Dupuytren’s contracture. HIV patients with advanced disease have DD in combination in up to 36% of cases. To our knowledge, this is the first case in which there is association of these three conditions in a single patient. Despite the evident need for research on PF, we believe that this paper may contribute to further elucidation about the disease.

REFERENCES

1. Fausto de Souza D, Micaelo L, Cuzzi T, Ramos-E-Silva M. Ledderhose disease: an unusual presentation. J Clin Aesthet Dermatol. 2010; 3 (9): 45-47.

2. Montgomery E, Lee JH, Abraham SC, Wu TT. Superficial fibromatoses are genetically distinct from deep fibromatoses. Mod Pathol. 2001; 14 (7): 695-701.

3. Souza BG, de Souza Júnior GZ, Rodrigues RM, Dias DS, de Oliveira VM. Surgical treatment of a case of Ledderhose’s disease: a safe plantar approach to subtotal fasciectomy. Case Rep Orthop. 2015; 2015: 509732.

4. Walker EA, Petscavage JM, Brian PL, Logie CI, Montini KM, Murphey MD. Imaging features of superficial and deep fibromatoses in the adult population. Sarcoma. 2012; 2012: 215810.

5. Zgonis T, Jolly GP, Polyzois V, Kanuck DM, Stamatis ED. Plantar fibromatosis. Clin Podiatr Med Surg. 2005; 22 (1): 11-18.

6. Gudmundsson KG, Jónsson T, Arngrímsson R. Association of Morbus Ledderhose with Dupuytren’s contracture. Foot Ankle Int. 2013; 34 (6): 841-845.

7. Hart MG, Hooper G. Clinical associations of Dupuytren’s disease. Postgrad Med J. 2005; 81 (957): 425-428.

8. Bower M, Nelson M, Gazzard BG. Dupuytren’s contractures in patients infected with HIV. BMJ. 1990; 300 (6718): 164-165.

9. Strzelczyk A, Vogt H, Hamer HM, Krämer G. Continuous phenobarbital treatment leads to recurrent plantar fibromatosis. Epilepsia. 2008; 49 (11): 1965-1968.

10. Bedi DG, Davidson DM. Plantar fibromatosis: most common sonographic appearance and variations. J Clin Ultrasound. 2001; 29 (9): 499-505.

11. Adib O, Noizet E, Croue A, Aubé C. Ledderhose’s disease: radiologic/pathologic correlation of superficial plantar fibromatosis. Diagn Interv Imaging. 2014; 95 (9): 893-896.

12. Lee TH, Wapner KL, Hecht PJ. Plantar fibromatosis. J Bone Joint Surg Am. 1993; 75 (7): 1080-1084.

13. van der Veer WM, Hamburg SM, de Gast A, Niessen FB. Recurrence of plantar fibromatosis after plantar fasciectomy: single-center long-term results. Plast Reconstr Surg. 2008; 122 (2): 486-491.

14. Degreef I, De Smet L. Risk factors in Dupuytren’s diathesis: is recurrence after surgery predictable? Acta Orthop Belg. 2011; 77 (1): 27-32.

15. Knobloch K, Vogt PM. High-energy focussed extracorporeal shockwave therapy reduces pain in plantar fibromatosis (Ledderhose’s disease). BMC Res Notes. 2012; 5: 542.