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2018, Number 2

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Rev Neurol Neurocir Psiquiat 2018; 46 (2)

Neuropsychological consequences of obstructive sleep apnea and therapeutic effect of constant positive airway pressure on cognitive performance

Lanzagorta N

Language: Spanish
References: 45
Page: 52-57
PDF size: 209.60 Kb.


ABSTRACT

One of the risk factors for the development of mild cognitive impairment (MCI) and dementia is obstructive sleep apnea (OSA). During episodes of apnea-hypopnea there are changes in the cerebral blood flow, fragmentation of sleep and molecular mechanisms that can affect both the structure of the brain and neuronal functioning, causing an impairment in cognitive functions. This study reviews the main neuropsychological functions affected by OSA such as attention, memory, executive functions, visual motor skills, motor functions and language. A qualitative review of the most relevant literature published in the past 20 years indexed in PubMed, Scopus and ScienceDirect was performed. Based on the findings of this review, it can be concluded that treatment of OSA with constant positive airway pressure (CPAP) is useful to improve both global functioning and performance in cognitive abilities as well as to delay the onset of MCI and dementia in adults.


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