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Academia Mexicana de Neurología, A.C.

2018, Number 5

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Rev Mex Neuroci 2018; 19 (5)

Epidemiological, clinical and laboratory characterization of bacterial meningitis in school hospital

Laínez-Mejía JL, Lázaro-Molina J, Yamileth-Ávila B

Language: Spanish
References: 30
Page: 19-26
PDF size: 208.66 Kb.


ABSTRACT

Introduction: Around the world, it is estimated that there were over 3,00,000 bacterial meningitis deaths in 2010. In Honduras, a study was carried out between 1983 and 1987 that evaluated the incidence of acute bacterial meningitis in adults at the Hospital Escuela, where 76 cases were observed, of which 75% were male. Objective: To analyze the epidemiological, clinical and laboratory characteristics in adult patients with bacterial meningitis treated in the emergency service of the University School Hospital in the years 2012-2015. Material and Methods: The sample was 78 clinical records. The data collection was obtained through the application of instruments, getting the information of the clinical files. Results: A prevalence of 45 (58%) male cases and 33 (42%) female cases were observed. The mean age was 53 years, with a higher frequency among patients aged 40–60 years; The most affected departments were Francisco Morazán and Choluteca with 45 (58%) and 10 (13%) respectively. The most frequent symptoms and signs have altered the state of consciousness with 51 (65%) cases, fever with 45 (58%) cases and headache with 42 (54%) cases. Positive cultures reported that 60% of the cases were caused by Streptococcus pneumoniae. Conclusion: The highest frequency was of male patients, with a mean age of 53 years and in 60% of positive cultures S. pneumoniae was isolated.


REFERENCES

  1. Gastón I, Muruzábal J, Quesada P, Maraví E. Infecciones del sistema nervioso central en urgencias. An Sist Sanit Navar. 2008;31 Suppl 1:99-113.

  2. Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2095-128.

  3. World Health Organization. Meningitis [citado el 12 de diciembre de 2016]. Disponible en: http://www.who.int/topics/meningitis/es/

  4. Bustillo Munguía JP. Meningitis aguda bacteriana del adulto en el bloque médica quirúrgico del Hospital Escuela en los años 1983-1987. Tegucigalpa. 1990. Disponible en: http://www.bvs.hn/cgi-bin/wxis.exe/iah/ scripts/?IsisScript=iah.xis&lang=es&base=bimena&nextAction=lnk&expr- Search=Juan%20and%20Pablo%20and%20Bustillo%20and%20Mungu% EDa&label=Juan%20and%20Pablo%20and%20Bustillo%20and%20 Mungu%EDa]

  5. Polanco Portillo BM, Pineda Estrada EJ. Estudio retrospectivo sobre meningitis bacteriana, tuberculosa, viral y micótica en el bloque médico quirúrgico Hospital Escuela. Enero de 1982 a diciembre de 1986. Tegucigalpa. 1987. Disponible en: http://www.bvs.hn/cgi-bin/wxis.exe/iah/ scripts/?IsisScript=iah.xis&lang=es&base=bimena&nextAction=lnk&expr- Search=Blanca%20and%20Miriam&label=Blanca%20and%20Miriam]

  6. Brouwer MC, Tunkel AR, van de Beek D. Epidemiology, diagnosis, and antimicrobial treatment of acute bacterial meningitis. Clin Microbiol Rev. 2010;23(3):467-92.

  7. Ayala M, Sousa LD, Romano LM, Zorrilla JP, Abut PÁ, Villegas J, et al. Efusión subdural como complicación de meningoencefalitis por Listeria monocytogenes. Neurología Argentina. 2011;3(2):138-9.

  8. McIntyre PB, O’Brien KL, Greenwood B, van de Beek D. Effect of vaccines on bacterial meningitis worldwide. Lancet. 2012;380(9854):1703-11.

  9. Garlicki AM, Jawien M, Pancewicz SA, Moniuszko-Malinowska A. Principles of diagnosis and treatment of bacterial purulent meningoencephalitis in adults. Przegl Epidemiol. 2015;69(2):303-7, 415-20.

  10. Van de Beek D, Brouwer MC, Thwaites GE, Tunkel AR. Advances in treatment of bacterial meningitis. Lancet. 2012;380(9854):1693-702.

  11. McGill F, Heyderman RS, Panagiotou S, Tunkel AR, Solomon T. Acute bacterial meningitis in adults. Lancet. 2016;388(10063):3036:47.

  12. Tebruegge M, Curtis N. Epidemiology, etiology, pathogenesis, and diagnosis of recurrent bacterial meningitis. Clin Microbiol Rev. 2009;22(1):183.

  13. Noguez IC, Melgoza MP, Hernández JAN. Frecuencia de agentes etiológicos identificados en pacientes con meningitis bacteriana aguda. Arch Inv Mat Inf. 2013;5(2):51-5.

  14. Van de Beek D, Gans J de, Spanjaard L, Weisfelt M, Reitsma JB, Vermeulen M. Clinical features and prognostic factors in adults with bacterial meningitis. N Engl J Med. 2004;351(18):1849-59.

  15. Castro JEL. Meningitis bacteriana y viral. Medicina Legal de Costa Rica. 2016;33(1):234-45.

  16. Conca N, Santolaya ME, Farfan MJ, Cofre F, Vergara A, Salazar L, et al. Etiologic diagnosis in meningitis and encephalitis molecular biology techniques. Rev Chil Pediatr. 2016;87(1):24-30.

  17. Julián-Jiménez A, Morales-Casado MI. Usefulness of blood and cerebrospinal fluid laboratory testing to predict bacterial meningitis in the emergency department. Neurologia. 2016. pii:S0213-4853(16)30085-8.

  18. Brouwer MC, Thwaites GE, Tunkel AR, van de Beek D. Dilemmas in the diagnosis of acute community-acquired bacterial meningitis. Lancet. 2012;380(9854):1684-92.

  19. Van de Beek D. Progress and challenges in bacterial meningitis. Lancet. 2012;380(9854):1623-4.

  20. Daugla DM, Gami JP, Gamougam K, Naibei N, Mbainadji L, Narbé M, et al. Effect of a serogroup A meningococcal conjugate vaccine (PsA–TT) on serogroup A meningococcal meningitis and carriage in Chad: A community study. Lancet. 2014;383(9911):40-7.

  21. Davenport MC, Del Valle, María de la Paz, Gallegos P, Kannemann AL, Bokser VS. Meningitis bacteriana: factores de riesgo para el desarrollo de complicaciones agudas. Archivos Argentinos de Pediatría. 2007; 105(5):405-10.

  22. Hadad P, Gualda A. Bad response to ceftriaxone treatment in Chilean adults with acute bacterial meningitis caused by Streptococcus pneumoniae. Rev Chilena Infectol. 2015;32(3):365-6.

  23. Stephens DS, Greenwood B, Brandtzaeg P. Epidemic meningitis, meningococcaemia, and Neisseria meningitidis. Lancet. 2007;369(9580): 2196-210.

  24. Thigpen MC, Whitney CG, Messonnier NE, Zell ER, Lynfield R, Hadler JL, et al. Bacterial meningitis in the United States, 1998-2007. N Engl J Med. 2011;364(21):2016-25.

  25. Xie Y, Tan Y, Chongsuvivatwong V, Wu X, Bi F, Hadler SC, et al. A Population-Based Acute Meningitis and Encephalitis Syndromes Surveillance in Guangxi, China, May 2007-June 2012. PLoS One. 2015; 10(12):e0144366.

  26. Jiménez Caballero PE, Serviá Candela M. Análisis descriptivo de las meningitis por Streptococcus pneumoniae en un hospital terciario. Neurología Argentina. 2012;4(1):6-10.

  27. Cruz E. EDUCACIÓN 2016: Instituto Nacional de Estadística Honduras, INE; 2016 [citado el 5 de diciembre de 2016]. Disponible en: http://www. ine.gob.hn/index.php?option=com_content&view=article&id=90

  28. Longo DL. Harrison. Principios de medicina interna. 18.ª ed. México: McGraw-Hill Interamericana; 2012. Disponible en: https://harrisonmedicina. mhmedical.com/book.aspx?bookid=865]

  29. Nkoumou MO, Betha G, Kombila M, Clevenbergh P. Bacterial and mycobacterial meningitis in HIV-positive compared with HIV-negative patients in an internal medicine ward in Libreville, Gabon. J Acquir Immune Defic Syndr. 2003;32(3):345-6. Disponible en: http://journals.lww.com/ jaids/Citation/2003/03010/Bacterial_and_Mycobacterial_Meningitis_ in.16.aspx

  30. Tique V, Alvis N, Parodi R, Bustos A, Mattar S. Meningitis agudas en Córdoba, Colombia 2002-2004. Rev Salud Pública. 2006;8:33-46.




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