2018, Number 6
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Med Int Mex 2018; 34 (6)
Strongyloidiasis disseminated in a patient with human immunodeficiency virus (HIV) infection
Rivas-Godoy AF, Izaguirre-González AI, Maradiaga-ReyesEF, Bu-Figueroa E, García-Aguilar JA
Language: Spanish
References: 16
Page: 973-977
PDF size: 411.34 Kb.
ABSTRACT
Strongyloides stercoralis is a parasite belonging to the group of nematodes, endemic
in rural regions of countries with tropical and subtropical climate where it can affect
between 30 and 100 million people. This infection is commonly asymptomatic
and may remain hidden for decades, but changes in the immune system favor the
development of a syndrome of hyperinfection or disseminated infection, with the
frequency estimated in chronic stages between 1.5 and 2.5%. This paper reports
the case of a female, 40 year-old patient, with HIV/AIDS and pulmonary tuberculosis,
who attended the emergency service of the University School Hospital,
Tegucigalpa, Honduras, with a history of diarrheic evacuations and abdominal pain
of one month of evolution, accompanied by vomiting preceded by nausea, fever
and weight loss approximately of 12 kg from the onset of symptoms. Laboratory
tests reported severe anemia, leukopenia and hydroelectrolytic disorders; general
examination of faeces revealed: larvae of
Strongyloides stercoralis, with abundant
polymorphonuclear leukocytes. Antibiotic treatment was started with sulfas, quinolones
and imidazoles, but the patient progressed unfavorably and died on the eighth
hospital day. It is important to consider the possibility of a disseminated infection
in patients with HIV/AIDS, because the delay in the beginning of the treatment and
a compromised immune system favor the proliferation of the parasite increasing
the mortality of the patient.
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