Despaigne SR, Benítez SE, Guzmán PN, Oliva CL, Acosta AN

Language: Spanish
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ABSTRACT

Introduction: Chronic obstructive pulmonary disease is an important cause of morbidity and mortality locally and worldwide.
Objective: To determine lethality predictive factors in patients with chronic obstructive pulmonary disease.
Methods: A study was carried out in cases and controls from the Intensive Care Unit from January 2012 to January 2016, using the multivariate logistic regression analysis. 100 patients constituted the sample. The patients included in the sample were alive or deceased with the diagnosis of chronic obstructive pulmonary disease. The main variables studied were comorbidity, need for invasive artificial mechanical ventilation, direct admission to the intensive care unit, chronic cor pulmonale, two or more previous admissions, and pulmonary parenchymal infection.
Results: Patients with a history of direct admission to the Intensive Care Unit had risk of dying (OR: 8,1 CI: 3,3- 19,8), two or more previous admissions (OR: 5, 8 IC: 2, 4- 13, 8), pulmonary parenchyma infection (OR: 19,1 CI: 6,4- 57,3), need for invasive artificial mechanical ventilation (OR: 23,2 CI: 7,9- 67,8) and cardiac arrhythmias (OR: 8,8 IC: 2,5- 30,2).
Conclusions: The factors of poor prognosis in the survival of patients discharged with chronic obstructive pulmonary disease were the need for invasive mechanical artificial ventilation, pulmonary parenchyma infection, history of direct admission and two or more previous admissions in the intensive care unit.