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2019, Number 1

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Rev Mex Anest 2019; 42 (1)

Nebulised ketamine for preventing postoperative pharyngeal pain

Franco-Cabrera M, Aguirre-Ibarra CP, Nava-López JA, Méndez-Hernández AZ, Duarte-Pérez KJ, Vargas-Aguilar DM, de la Cajiga-León A

Language: Spanish
References: 92
Page: 7-18
PDF size: 264.67 Kb.


ABSTRACT

Introduction: The postoperative sore throat is a frequent complication, characterized by odynophagia after endotracheal intubation. Objective: To compare nebulized ketamine in the preoperative period against nebulized placebo for the reduction of the postoperative sore throat on elective surgery under general anesthesia. Material and methods: We performed an experimental, prospective, randomized, double blind study; conducted from February to July 2016. Patients were randomly assigned into two groups: group K: preoperative nebulized ketamine (50 mg: 1 mL of ketamine + 2 mL of saline solution 0.9%) against group P: placebo (nebulization of 3 mL saline solution 0.9%). We collected vital signs as well as symptoms and intensity of postoperative sore throat according to the analog numeric scale at the first and forth postoperative hours Results: The use of nebulized ketamine does not represent a statistically significant difference compared to placebo for postoperative sore throat. The incidence of postoperative sore throat in our study was of 59.29%. Conclusions: We need further studies of nebulized ketamine in the Mexican population, as well as a larger study to determine the gold standard for the treatment of POST.


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