medigraphic.com
Instituto Nacional de Salud Pública

2019, Number 1

<< Back

salud publica mex 2019; 61 (1)

The impact of the HPV test in screening programs in Latin America: The case of Argentina

Arrossi S

Language: Spanish
References: 45
Page: 86-94
PDF size: 326.91 Kb.


ABSTRACT

Objective. To assess the impact of HPV testing on longstanding problems faced by screening programs in Latin America, using the case of the Jujuy Demonstration Project (JDP) in Argentina. Materials and methods. The study measured the level of impact produced by the introduction of HPV-testing on problems faced by cytology programs by analyzing modifications on specific problems produced during the JDP. Impact was classified as direct/indirect, and positive/ negative. Results. Direct/positive impact was found in issues concerning age and screening frequency, cytology laboratories and screening sensitivity, and low coverage. Direct/negative impact was mainly related to the adherence to triage cytology by HPV+ women with self-collected-tests, and the delivery and labelling of samples. Indirect impact of HPV-Test was mostly positive, and related to the programmatic reorganization which was facilitated by the introduction of HPV testing. Conclusions. HPV testing provides an opportunity window for improving primary screening, but does not solve programmatic problems.


REFERENCES

  1. Lazcano-Ponce EC, Moss S, Alonso de Ruiz P, Salmerón-Castro J, Hernández-Ávila M. Cervical cancer screening in developing countries: why is it ineffective? The case of Mexico. Arch Med Res.1999;30(3):240-50. https://doi.org/10.1016/S0188-0128(99)00006-8

  2. Sankaranarayan R, Budukh AM, Rajkumar R. Effective screening programmes for cervical cancer in low-and middle- income developing countries. Bull World Health Organ.2001;79(10):954-62.

  3. Murillo R, Almonte M, Pereira A, Ferrer E, Gamboa OA, Jerónimo J, et al. Cervical cancer screening programs in Latin America and the Caribbean. Vaccine. 2008;26(suppl 11)L37-48. https://doi.org/10.1016/j. vaccine.2008.06.013

  4. Arrossi S, Paolino M, Sankaranarayanan R. Challenges faced by cervical cancer prevention programs in developing countries: a situational analysis of program organization in Argentina. Rev Panam Salud Publica. 2010;28(4):249-57. https://doi.org/10.1590/S1020-49892010001000003

  5. Cuzick J, Szarewski A, Terry G, Ho L, Hanby A, Maddox P, et al. Human papillomavirus testing in primary cervical screening. Lancet.1995; 345(8964):1533-6. https://doi.org/10.1016/S0140-6736(95)91086-7

  6. Salmerón J, Lazcano-Ponce E, Lorincz A, Hernández M, Hernández P, Leyva A, et al. Comparison of HPV-based assays with Papanicolaou smears for cervical cancer screening in Morelos State, Mexico. Cancer Causes Control. 2003;14(6):505-12. https://doi.org/10.1023/A:1024806707399

  7. Herrero R, Ferreccio C, Salmerón J, Almonte M, Sánchez GI, Lazcano- Ponce E, et al. New approaches to cervical cancer screening in Latin America and the Caribbean. Vaccine. 2008;26(suppl 11):L49-58. https://doi. org/10.1016/j.vaccine.2008.05.025

  8. Castle PE, de Sanjosé S, Qjao Y, Belinsone JL, Lazcano-Ponce E, Kinney W. Introduction Human Papillomavirus DNA screening in the world: 15 years of experience. Vaccine. 2012;30(suppl 5):F117-22. https://doi. org/10.1016/j.vaccine.2012.05.071

  9. Organización Mundial de la Salud. Directrices de la OPS/OMS sobre detección y tratamiento de las lesiones precancerosas para la prevención del cáncer cervicouterino. Washington DC: OPS, 2013.

  10. Cervical Cancer Action [Internet]. Cervical Cancer Action. Maps. Global progress in HPV DNA testing for cervical cancer screening; [citado nov 13, 2017]. Disponible en: http://www.cervicalcanceraction.org/ comments/maps.php

  11. Jeronimo J, Holme F, Slavkovsky R, Camel C. Implementation of HPV testing in Latin America. J Clin Virol. 2016;76(suppl 1):S69-73. https://doi. org/10.1016/j.jcv.2015.11.035

  12. Sankaranarayanan R, Nene BM, Shastri SS, Jayant K, Muwonge R, Budukh AM. HPV screening for cervical cancer in rural India. N Eng J Med. 2009;360:1385-94. https://doi.org/10.1056/NEJMoa0808516

  13. Bingham A, Bishop A, Coffey P, Winkler J, Bradley J, Dzuba I, et al. Factors affecting utilization of cervical cancer prevention services in low-resource settings. Salud Publica Mex. 2003;45(3):408-16. https://doi. org/10.1590/S0036-36342003000900015

  14. Turner S, Ramsay A, Perry C, Boaden R, McKevitt C, Morris S, et al. Lessons for major system change: centralization of stroke services in two metropolitan areas of England. J Health Sery Res Policy. 2016;21(3):156-65. https://doi.org/10.1177/1355819615626189

  15. Arrossi S, Thouyaret L, Laudi R, Marin O, Ramírez J, Paolino M, et al. Implementation of HPV-testing for cervical cancer screening in programmatic contexts: the Jujuy demonstration project in Argentina. Int J Cancer.2015;137(7):1709-18. https://doi.org/10.1002/ijc.29530

  16. Arrossi S, Paolino M, Thouyaret L, Laudi R, Campanera A. Evaluation of scaling-up of HPV self-collection offered by community health workers at home visits to increase screening among socially vulnerable underscreened women in Jujuy Province, Argentina. Implement Sci. 2017;12:17. https://doi.org/10.1186/s13012-017-0548-1

  17. Arrossi S, Thouyaret L, Paul L. Prevención del cáncer cervicouterino. Recomendaciones para el tamizaje, seguimiento y tratamiento de mujeres en el marco de programas de tamizaje basados en el test de VPH. Actualización 2015. Buenos Aires: INC-MSAL, 2015.

  18. Herrero R, Brinton LA, Reeves WC, Brenes MM, Tenorio F, de Britton RC, et al. The risk factors of invasive carcinoma of the cervix uteri in Latin America. Bol Oficina Sanit Panam. 1990;109(1):6-26.

  19. Bosch FX, Muñoz N, de Sanjosé S, Izarzugaza I, Gili M, Viladiu P, et al. Risk factors for cervical cancer in Colombia and Spain. Int J Cancer. 1992;52(5):750-8. https://doi.org/10.1002/ijc.2910520514

  20. Arrossi S, Ramos S, Paolino M, Sankaranarayanan R. Social inequality in Pap smear coverage: identifying under-users of cervical cancer screening in Argentina. Reprod Health Matters. 2008;16(32)50-8. https://doi. org/10.1016/S0968-8080(08)32410-0

  21. Lazcano-Ponce EC, Castro R, Allen B, Nájera P, Alonso de Ruiz PA, Hernández-Ávila M. Barriers to early detection of cervical-uterine cancer in Mexico. J Womens Health. 1999;8(3):399-408. https://doi.org/10.1089/ jwh.1999.8.399

  22. Aguilar-Perez JA, Leyva-López AG, Angulo-Nájera D, Salinas A, Lazcano- Ponce EC. Cervical cancer screening: knowledge of Pap smear benefits and utilization in Mexico. Rev Saude Publica.2003;37(1):100-6.

  23. Dzuba IG, Calderon R, Bliesner S, Luciani S, Amado F, Jacob M, et al. A participatory assessment to identify strategies for improved cervical cancer prevention and treatment in Bolivia. Rev Panam Salud Publica. 2005;18(1):53-63. https://doi.org/10.1590/S1020-49892005000600012

  24. Ramos S, Pantelides EA. Dificultades en la prevención secundario del cáncer de cuello de útero: las mujeres y los médicos frente a una citología cervical de resultado positivo. Buenos Aires: CECES, 1990.

  25. Paolino M, Arrossi S. Women’s knowledge about cervical cancer, Pap smear and human papillomavirus and its relation to screening in Argentina. Women Health. 2011;51(1):72-87. https://doi.org/10.1080/036 30242.2010.542547

  26. Paz-Soldán VA, Nussbaum L, Bayer AM, Cabrera L. Low knowledge of cervical cancer and cervical pap smears among women in Peru, and their ideas of how this could be improved. Int Q Community Health Educ. 2011;31(3):245-63. https://doi.org/10.2190/IQ.31.3.d

  27. Lazcano-Ponce E, Alonso P, Ruiz-Moreno JA, Hernández-Ávila M. Recommendations for cervical cancer screening programs in developing countries. The need for equity and technological development. Salud Publica Mex. 2003;45(3):449-62. https://doi.org/10.1590/S0036- 36342003000900020

  28. Murillo R, Wiesner C, Cendales R, Piñeros M, Tovar S. Comprehensive evaluation of cervical cancer screening programs: the case of Colombia. Salud Publica Mex. 2011;53(6):469-77.

  29. Paolino M, Pantelides E, Bruno M, Maceira V, Peña L, Godoy J, et al. Determinantes sociales del seguimiento y tratamiento de mujeres con Pap anormal en Avellaneda, provincia de Buenos Aires. Rev Argent Salud Pública. 2011;2(8):21-7.

  30. Lazcano-Ponce EC, Moss S, Cruz-Valdez A, Alonso de Ruiz P, Casares- Queralt S, Martínez-León CJ, et al. The factors that determine participation in cervical cancer screening in the state of Morelos. Salud Publica Mex.1999;41(4):278-85.

  31. Frenk J, González-Pier E, Gómez-Dantés O, Lezana MA, Knaul FM. Comprehensive reform to improve health system performance in Mexico. Lancet. 2006;368(9546):1524-34. https://doi.org/10.1016/S0140- 6736(06)69564-0

  32. Arrossi S, Paolino M. Proyecto para el mejoramiento del Programa Nacional de Prevención de Cáncer de Cuello Uterino en Argentina. Informe final: diagnóstico de situación del Programa Nacional y Programas Provinciales. Buenos Aires: OPS, 2008.

  33. Lazcano-Ponce EC, Alonso de Ruiz P, López-Carrillo L, Nájera-Aguilar P, Avila-Ceniceros R, Escandón-Romero C, et al. Validity and reproducibility of cytologic diagnosis in a simple of cervical cancer screening centers in Mexico. Acta Cytol.1997;41(2):277-84. https://doi.org/10.1159/000332512

  34. Lazcano-Ponce EC, Alonso de Ruiz P, Martinez-Arias C, Murguia- Riechers L. Reproducibility study of cervical cytopathology in Mexico: a need for regulation and professional accreditation. Diagn Cytopathol. 1997;17(1):20-4. https://doi.org/10.1002/(SICI)1097- 0339(199707)17:1<20::AID-DC4>3.0.CO;2-T

  35. Lazcano-Ponce EC, Alonso de Ruiz P, López-Carrillo L, Vázquez- Manríquez ME, Hernández-Ávila M. Quality control study on negative gynecological cytology in Mexico. Diagn Cytopathol.1994;10(1):10-4. https://doi.org/10.1002/dc.2840100104

  36. Lazcano-Ponce EC, de Ruiz PA, Martínez Arias C, Murguía-Riechers L. Diagnostic concordance in gynecologyc cytology. Rev Invest Clin.1997;49(2):111-6.

  37. Lazcano-Ponce E, Allen-Leigh B. Innovation in cervical prevention and control in Mexico. Arch Med Res. 2009;40(6)486-92. https://doi. org/10.1016/j.arcmed.2009.07.007

  38. Zubizarreta EH, Poitevin A, Levin CV. Overview of radiotherapy resources in Latin America: a survey by the Internationl Atomic Energy Agency (IAEA). Radiother Oncol.2004;73(1):97-100. https://doi.org/10.1016/j. radonc.2004.07.022

  39. Arrossi S, Matos E, Zengarini N, Roth B, Sankaranarayanan R, Parkin M. The socio-economic impact of cervical cancer on patients and their families in Argentina, and its influence on radiotherapy compliance. Results from a cross-sectional study. Gynecol Oncol. 2007;105(2):335-40. https:// doi.org/10.1016/j.ygyno.2006.12.010

  40. Arrossi S, Sankaranarayanan R, Parkin DM. Incidence and mortality of cervical cancer in Latin America. Salud Publica Mex. 2003;45(3):306-14. https://doi.org/10.1590/S0036-36342003000900004

  41. Ortega-González P, González-Bravo MS, Jiménez-Muñoz-Ledo G, Macías AE. Abnormalities in cervical smears stored in plastic bags: potential cause of false negatives. Rev Invest Clin. 2011;63(3):263-7.

  42. Arrossi S, Thouyaret L, Herrero R, Campanera A, Magdaleno A, Cuberli M, et al. Effect of self-collection of HPV DNA offered by community health workers at home visits on uptake of screening for cervical cancer (the EMA study): a population-based cluster-randomised trial. Lancet Glob Health. 2015;3(2):e85-94. https://doi.org/10.1016/S2214-109X(14)70354-7

  43. Arrossi S, Ramos S, Straw C, Thouyaret L, Orellana L. HPV testing: a mixed-method approach to understand why women prefer self-collection in a middle-income country. BMC Public Health. 2016;16:832. https://doi. org/10.1186/s12889-016-3474-2

  44. Mazzadi A, Paolino M, Arrossi S. Aceptabilidad y conocimientos sobre la vacunación contra el virus del papiloma humano (VPH) en médicos ginecólogos de la Argentina. Salud Publica Mex. 2012;54(5):515-22. https:// doi.org/10.1590/S0036-36342012000500008

  45. Solar O, Irwin A. A conceptual framework for action on the social determinants of health. Social Determinants of Health Discussion Paper 2 (Policy and Practice). Geneva: WHO, 2010.




2020     |     www.medigraphic.com