Torres ZAJ, Montenego TDF, Esteban AJ, Borges ML, Agramonte LOM

Language: Spanish
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ABSTRACT

Introduction: Sickle cell disease causes cardiovascular dysfunction in many cases, so the evaluation of this is essential.
Objective: To evaluate echocardiographically the systolic and diastolic function of the left ventricle in Cuban patients with sickle cell disease.
Material and Method: Prospective descriptive study in the 31 patients with sickle cell disease and 52 controls attended in the Institute of Cardiology and Cardiovascular Surgery from June 2017 to January 2018, to which cardiovascular function was evaluated. Everyone gave their informed consent to participate. Sociodemographic, clinical and echocardiographic variables were evaluated. Frequency analyzes were performed, in addition to using the Chi-squared and Student's t tests. In all cases, the presence of significant differences was delimited for a level of significance p <0.05.
Results: In the sickle cell, 52% had ages between 41-60 years, the body mass index was normal, as well as the systolic and diastolic blood pressures. The mean hemoglobin was 7.7 ± 1.9 g / L and the oxygen saturation was 95.6 ± 4.5%. Sicklemia was represented by 77.4%. The mean left ventricular ejection fraction was 66.33 ± 4.30%, and both end-diastolic and end-systolic volume were normal. 58% of sickle cell patients had normal ventricular geometry, and 25.9% had eccentric hypertrophy. The diastolic function was conserved in 74.2%, and the heart rate, cardiac output and cardiac index were normal.
Conclusions: It was demonstrated that the sicklemic patients had preserved systolic and diastolic function of the left ventricle, which suggests their good cardiovascular health.