2018, Number 4
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Rev Salud Publica Nutr 2018; 17 (4)
Intervención nutricional con omega 3 en un grupo de pacientes con diagnóstico de Trastorno del Espectro Autista (TEA)
Serrato SKA, Bazaldúa LV, Garza SG, Cuellar RS, Márquez ZL, Sánchez PMA
Language: Spanish
References: 15
Page: 27-33
PDF size: 232.48 Kb.
ABSTRACT
Introduction: autism spectrum disorders affects social interaction, and behavior. Several studies describe a variety of
therapies including gluten-free diet and casein and supplementation with omega-3 fatty acids.
Objective: To evaluate the
effect of a diet without gluten and casein, supplemented with omega-3 fatty acids in Autistic Spectrum Disorder.
Methods:
non randomized controlled experimental study conducted during eight weeks in fifteen children diagnosed with ASD in an age
range of 3-12 years, with nutritional evaluation and the CARS scale at the beginning and end of the study, were divided into
three groups, group A: diet without gluten and casein, group B: diet without gluten and casein plus omega-3 in a dose of 1.2
g / d and group C: control without diet and without supplementation. Performing statistical analysis with the statistical
program MEDCALC
®.
Results: Of 15 subjects, 20% belonged to the female gender while 80% to the male sex with an average
age of 7 years. When comparing the behavior, a significant difference was observed (p = 0.0006) in group B.
Conclusions: The
diet without gluten and casein and those with omega-3 fatty acids can be an effective nutritional therapy to improve behavior.
REFERENCES
Amminger, P. G., Berger, G. E., Schäfer, M. R., Klier, C., Friedrich, M. H., & Feucht, M. (2007). Omega-3 Fatty Acids Supplementation in Children with Autism: A Double-blind Randomized, Placebo-controlled Pilot Study. En Biol Psychiatry , 61, 551-553. doi: 10.1016/j.biopsych.2006.05.007.
Alvarez, I., Camacho Arroyo, I. (2010). Bases Geneticas del Autismo. En Acta Pediatr Mex, 31, 22-28. doi: 10.18233/APM31No1pp22-28.
Belmaker, R. H., & Meiri, G. (2014). Comprehensive Guide to Autism. doi: 10.1007/978-1-4614-4788-7.
Bent, S., Bertoglio, K., Ashwood, P., Bostrom, A., & Hendren, R. L. (2011). A Pilot Randomized Controlled Trial of Omega-3 Fatty Acids for Autism Spectrum Disorder. En Journal of Autism and Developmental Disorders , 41, 545-554. doi: 10.1007/s10803-010- 1078-8.
Harrison Elder, J., Shankar, M., Shuster, J., Theriaque, D., Burns, S., &Sherril, L. (2006). The Gluten-Free, Casein-Free Diet In Autism: Results of A Preliminary Double Blind Clinical Trial. En Journal of Autims and Developmental Disorders, 36, 413-420. doi: 10.1007/s10803-006-0079-0.
Harris, C., Card, B. (2012). A pilot study to evaluate nutritional influences on gastrointestinal symptoms and behavior patterns in children with Autism Sprectrum Disorder. En Complementary Therapies in Medicine, 20, 437-440. doi: 10.1016/j.ctim.2012.08.004.
James, S., Montgomery, P., Williams, K. (2011). Omega- 3 fatty acids supplementation for autism spectrum disorders (ASD). Cochrane Database of Systematic Reviews, 11, 1-24. Recuperado de: https://www.cochranelibrary.com/cdsr/doi/10.1002/14 651858.CD007992.pub2/full.
Mankad, D., Dupuis, A., Smile, S., Roberts, W., Brian, J., Lui, T., y otros. (2015). A randomized, placebo controlled trial of omega-3 fatty acids in the treatment of young children with autism. En Molecular Autism, 6, 1-11. doi: 10.1186/s13229-015-0010-7.
Marí-Bauset, S., Zazpe, I., Mari-Sanchis, A., Llopis- González, A., & Suárez-Varela, M. (2014). Evidence of the gluten free and casein free diet in autism spectrum dosirders (ADS): a systematic review. En Journal of child neurology, 29, 1718-1727. doi: 10.1177/0883073814531330
Mazahery, H., Stonehouse, W., Delshad, M. (2017). Relationship between Long Chain n-3 Polyunsaturated Fatty Acids and Autism Spectrum Disorder: Systematic Review and Meta-Analysis of Case- Control and Randomised Controlled Trials. Nutrients, 9, 1-32. doi: 10.3390/nu9020155.
Millward, C., Ferriter, M., Calver, S. J., & Connell-Jones, G. G. (2014). Gluten- and casein-free diets for autistic spectrum disorder. En Cochrane Database Syst Rev, 2- 29. doi: 10.1002/14651858.
Oviedo, N., Manuel, L., de la Chesnaye, E., Guerra, C. (2015). Aspectos genéticos y neuroendocrinos en el trastorno del espectro autista. En Bol Med Hosp Infant Mex, 72, 5-14. doi: 10.1016/j.bmhimx.2015.01.010.
Politi, P., Cena, H., & Emanuele, E. (2011). Handbook of Behavior, Food and Nutrition. doi: 10.1007/978-0- 387-92271-3_116.
Seung, H., Rogalski, Y., Shankar, M. (2007). Journal of medical speech-lenguage pathology. Recuperado de: https://www.researchgate.net/publication/268277130.
Schopler, E., Reichler, R. J., DeVellis, R. F., & Daly, K. (1980). Toward Objective Classification of Childhood Autism: Childhood Autism Rating Scale (CARS). Journal of Autism and Developmental Disorders , 10, 92-103. doi: 10.1007/BF02408436.