2018, Number 3
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Rev Latin Infect Pediatr 2018; 31 (3)
Cardiac’s complications in mexican childs with Kawasaki disease. Multicentric study of the Kawasaki network of Mexico
Coria LJJ, Ramírez BD, Sotelo CN, Díaz LJL, Enríquez CO, Unda GJJ, Ramírez RR, Martínez ML, Díaz TA, Jiménez JRN, Reyes LA, Enciso PS, Gutiérrez CM
Language: Spanish
References: 22
Page: 110-117
PDF size: 194.28 Kb.
ABSTRACT
Objectives: To describe the clinical features and progression of cardiac complications in children with Kawasaki disease.
Material and methods: We reviewed clinical records of children with this diagnosis seen in nine hospitals in Mexico from January 2008 to December 2012 with some cardiac complication.
Results: Out of 179 cases, 86 presented cardiac complications. Male (65%) versus female (35%) predominate, with a 2:1 ratio. The age range varies from 5 to 213 months. Kawasaki’s kind corresponded 68.6% to the classic and 31.4% to the non-classical. Of the coronary complications that stood out: coronary ectasia, 82 (95.3%) events, and aneurysmal lesions in 75 patients (87.2%). A total of 56 cases (65.11%) of non-coronary cases were registered, highlighting pericardial effusion, followed by valvulitis in 19 (22%) and 15 (17.4%) patients, among others.
Analysis: There was a higher percentage of aneurysmal complications in our series than in the literature, but the evolution to resolution or regression behaved as described in the literature. Unlike the non-coronary complications that were minor in our analysis.
Conclusions: Cardiac complications represent the main cause of morbidity and mortality in both the acute and subacute phases of the disease, which is why echocardiograms and electrocardiograms are important tools for early and timely diagnosis when there is a suspicion of Kawasaki.
REFERENCES
Newburger JW, Takahashi M, Gerber MA, Gewitz MH, Tani Ll Y, Burns JC et al. Diagnosis, treatment, and long-term management of Kawasaki disease a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis and Kawasaki disease, council on cardiovascular disease in the young, American Heart Association. Circulation. 2004; 110: (17): 2747-2771.
Rodríguez HR, Carbajal RL, Zarco RJ, Barrios FR. Síndrome de Kawasaki. Paciente de menor edad reportado en la casuística del Hospital Infantil de México Federico Gómez y revisión de la literatura. Bol Med Hosp Infant Mex. 2002; 59 (12): 430-435.
Saulsbury F. Kawasaki syndrome. In: Mandell GL, Douglas RG, Bennett JE, Dolin R. Mandell, Douglas, and Bennett’s. Principles and practice of infectious disease. 6th ed. Ed. New York: Churchill Livingston; 2005. pp. 2983-6.
Falcini F. Kawasaki disease. Curr Opin Rheumatol. 2006; 18 (1): 33-38.
Díaz RA, Aránguiz E, Pedemonte O, Silva D, Villablanca S, Torres H y cols. Enfermedad coronaria aneurismática severa en un adolescente con angina de esfuerzo secundaria a enfermedad de Kawasaki no diagnosticada previamente. Rev Méd Chile. 2007; 135 (9): 1182-1185.
Falcini F, Ozen S, Magni-Manzoni S, Candelli M, Ricci L, Martini G, et al. Discrimination between incomplete and atypical Kawasaki syndrome versus other febrile diseases in childhood: results from an international registry-based study. Clin Exp Rheumatol. 2012; 30: 799-804.
Vargas-Barrón J, Andrade-Freire A, Attie F. Diagnóstico con ecocardiografía bidimensional y Doppler de aneurisma coronario en un niño mexicano con enfermedad de Kawasaki. Arch Inst Cardiol Mex. 1988; 58 (3): 227-229.
Beth MF, Newburger JW. Kawasaki disease. Pediatrics in review. 2013; 34 (4): 151.
Huo Ho.Ch, Yang KD, Chang WC, Ger LP, Hsieh KS. Kawasaki disease: an update on diagnosis and treatment. Pediatr Neonatol. 2012; 53 (1): 4-11.
Heuclin T, Dubos F, Hue V, Godart F, Francart C, Vincent P et al. Increased detection rate of Kawasaki disease using new diagnostic algorithm, including early use of echocardiography. J Pediatr. 2009; 155 (5): 695-699.
Frenkel SM, Ocaña GL, Bautista SA, Cortina MR, Cortina JW. Enfermedad de Kawasaki: experiencia con ocho casos del Centro Médico ABC. Anal Med Hosp ABC. 2004; 49(2):66-72.
Sotelo N, González LA. Kawasaki disease: a rare pediatric pathology in Mexico. Twenty cases report from the Hospital Infantil del Estado de Sonora. Arch Cardiol Mex. 2007; 77(4): 299-307.
Quezada-Chavarría G, Ramírez-Serrallonga R, Quezada-Cuevas SE, Salazar-Salas J, Fernández-Gómez I, Esparza-Pérez RI. Enfermedad de Kawasaki: análisis de 17 casos. Rev Med Inst Mex Seguro Soc. 2009; 47 (1): 61-64.
Gil MV, Flores EM, Beirana LG, Miranda MG, Huerta GC, Solórzano FS. Enfermedad de Kawasaki: comportamiento clínico y complicaciones cardiovasculares en niños atendidos en un hospital de tercer nivel. Arch Cardiol Mex. 2009; 79 (1): 11-17.
Morales-Quispe JA, Espinoza-Zavaleta N, Caballero-caballero R, Garcia-López JJ, Rodríguez-Quezada JM, Betánzos-Rodríguez L. Enfermedad de Kawasaki: evolución y complicaciones cardiovasculares en niños. Rev Med Inst Mex Seguro Soc. 2011; 49 (3): 295-300.
Rowley AH, Shulman ST. Kawasaki síndrome. Clin Microbiol Rev. 1998; 11 (3): 405-414.
McCrindle BW. Long-term management of Kawasaki disease. implication for the adult patient. Pediatr Neonatol. 2013; 20: 1-10.
Fukunaga S, Egashira A, Arinaga K, Akasu I, Kai E, Higashi T et al. Aortic valve replacement for aortic regurgitation due to Kawasaki disease: report of two cases. J Heart Valve Dis. 1996; 5 (2): 231-234.
Enfermedad de Kawasaki. Texas Heart Institute. Octubre 2015. www.texasheart.org/HIC/Topics_Esp/Cond/kawasaki_disease_sp.cfm
Kuramochi Y, Takechi N, Ohkubo T, Ogawa S. Longitudinal estimation of signal-averaged electrocardiograms in patients With Kawasaki disease. Pediatr Int. 2002; 44: 12-17.
Harada M, Yokouchi Y, Oharaseki T, Matsui K, Tobayama H, Tanaka N et al. Histopahological characteristics of myocardiytis in acute-pjase Kawasaki disease. Histopathology. 2012; 61: 1156-1167.
Iemura M, Ishii M, Sugimura T, Akagi T, Kato H. Long Term consequences of regressed coronary aneurysms after Kawasaki disease: Vascular wall morphology and function. Heart. 2000; 83: 307-311.