2018, Number 3
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Acta Pediatr Mex 2018; 39 (3)
Comparison of PAS and Lintula score in diagnosis suspect of appendicitis in children
Mujica-Guevara JA, Pierdant-Pérez M, Gordillo-Moscoso AA, Martínez-Martínez MU, Ramírez-Meléndez R
Language: Spanish
References: 21
Page: 209-215
PDF size: 463.10 Kb.
ABSTRACT
Introduction: Acute appendicitis is the leading cause of abdominal surgery in children.
It is sometimes difficult to distinguish appendicitis from other conditions, which
can lead to delayed diagnosis. The pediatric score for appendicitis and the Lintula score
are scoring systems based on the presence or absence of symptoms and signs that have
been validated in the pediatric population. There are no prospective studies in the same
population group that would inform us which would be most useful in evaluating the
child with suspected appendicitis.
Objectives: The purpose of this study was to compare the results of the Lintula (SL)
and Pediatric Appendicitis Score (PAS) systems and to establish the best score foracute
appendicitisdiagnosis in children.
Methods: We prospectively evaluated children of 4 to 15 years old with abdominal
pain and suspected appendicitis who were admitted to the pediatric emergency department
of a secondarylevel hospital, in the period from February to August 2015. Both
scores were rated in each patient, definitive diagnosis was pathological or the follow up.
Results: 100 patients were included, 47% confirmed appendicitis. LS average in patients
without appendicitis was 12.5 (SD 6.2) and 28.8 (SD 5.2) for appendicitis cases.
(p‹0.001). The PAS average score was 4.3 (SD 2.1) for patients without appendicitis
and 8.3 (SD 1.5) for appendicitis cases (p ‹0.001). Based on the ROC curve analysis,
the best cutoff point was 20 for SL and 6 for PAS. SL sensitivity was 89.4%, specificity
90.6%. AUC 0.942. PAS yielded 95.7%, specificity 75.5% sensitivity. AUC 0.924. We
found no significant differences between both scores.
Conclusions: Both scores have an appropriate sensitivity and specificity;therefore,
its use should be encouraged in the evaluation of children with suspected appendicitis
in our population.
REFERENCES
Yoldas O, Karaca T, Tez M. External validation of Lintula score in Turkish acute appendicitis patients. Int J Surg. 2012;10(1):25-7.
Wu H-P, Chen C-Y, Kuo I-T, Wu Y-K, Fu Y-C. Diagnostic values of a single serum biomarker at different time points compared with Alvarado score and imaging examinations in pediatric appendicitis. J Surg Res. 2012;174(2):272-7.
Maguire JL, Kulik DM, Laupacis A, Kuppermann N, Uleryk EM, Parkin PC. Clinical prediction rules for children: a systematic review. Pediatrics. 2011;128(3):e666-77.
Kulik DM, Uleryk EM, Maguire JL. Does this child have appendicitis? A systematic review of clinical prediction rules for children with acute abdominal pain. J Clin Epidemiol. 2013;66(1):95-104.
Douglas C, Macpherson N, Davidson P, Gani J. Randomized controlled trial of ultrasonography in diagnosis of acute appendicitis, incorporating the Alvarado score. BMJ. 2000;321:919-22.
Sencan A, Aksoy N, Yıldız M, Okur Ö, Demircan Y, Karaca I. The evaluation of the validity of Alvarado, Eskelinen, Lintula and Ohmann scoring systems in diagnosing acute appendicitis in children. Pediatr Surg Int. 2014;30(3):317-21.
Schneider C, Kharbanda A, Bachur R. Evaluating appendicitis scoring systems using a prospective pediatric cohort. Ann Emerg Med. 2007;49(6):778-784.
Samuel M. Pediatric appendicitis score. J Pediatr Surg. 2002;37(6):877-81.
Lintula H, Pesonen E, Kokki H, Vanamo K, Eskelinen M. A diagnostic score for children with suspected appendicitis. Langenbecks Arch Surg. 2005;390(2):164-70.
Lintula H, Kokki H, Kettunen R, Eskelinen M. Appendicitis score for children with suspected appendicitis. A randomized clinical trial. Langenbecks Arch Surg. 2009;394(6):999-1004.
Carley S, Dosman S, Jones SR, Harrison M. Simple nomograms to calculate sample size in diagnostic studies. Emerg Med J. 2005;22(3):180-1.
Sánchez Pedraza, Ricardo Echevarry Road J. Aspectos sobre diseño y tamaño de muestra en estudios de pruebas diagnósticas. Rev Fac Med. 2001;49(3):175-80.
Santillanes G, Simms S, Gausche-Hill M, Diament M, Putnam B, Renslo R, et al. Prospective evaluation of a clinical practice guideline for diagnosis of appendicitis in children. Acad Emerg Med. 2012;19(8):886-93.
Sencan A, Aksoy N, Yıldız M, Okur Ö, Demircan Y, Karaca I. The evaluation of the validity of Alvarado, Eskelinen, Lintula and Ohmann scoring systems in diagnosing acute appendicitis in children. Pediatr SurgInt. 2014;30(3):317-21.
Bhatt M, Joseph L, Ducharme FM, Dougherty G, McGillivray D. Prospective validation of the pediatric appendicitis score in a Canadian pediatric emergency department. Acad Emerg Med. 2009;16(7):591-6.
Escriba A, Gamell AM, Ferna Y, Mari J. Prospective Validation of Two Systems of Classification for the Diagnosis of Acute Appendicitis. Pediatr Emerg Care. 2011;27(3):165-9.
Goldman RD, Carter S, Stephens D, Antoon R, Mounstephen W, Langer JC, et al. Prospective validation of the pediatric appendicitis score. J Pediatr. 2008;153(2):278-82.
Mandeville K, Pottker T, Bulloch B, Liu J. Using appendicitis scores in the pediatric ED. Am J Emerg Med. 2011;29(9):972-7.
Ebell MH, Shinholser J. What Are the Most Clinically Useful Cutoffs for the Alvarado and Pediatric Appendicitis Scores? A Systematic Review. Ann Emerg Med. 2014;64(4):365-72.
Pogoreli Z, Rak S, Mrkli I, Juri I. Prospective Validation of Alvarado Score and Pediatric Appendicitis Score for the Diagnosis of Acute Appendicitis in Children. Pediatr Emerg Care. 2015;31(3):164-8.
Tlacuilo-Parra A, Hernández-Hernández A, Ambriz- González G, Venegas-Dávalos M, Gutiérrez-Hermosillo V, Guevara-Gutiérrez E. Costos de tratamiento de la apendicitis mediante grupos relacionados con el diagnóstico en un tercer nivel de atención pediátrica. Cir Cir. 2014;82(6):628-36.