González-Díaz E, Cruz-Neri RU, Morfín-Otero M, Álvarez-Martínez M, Rimoldi-Carbajal V, Pérez-Gómez HR, Gómez- Quiroz P, Vázquez-León M, Castillo-Moran MA, León-Garnica G, Petersen-Morfín S, Rodríguez-Noriega E

Language: Spanish
References: 53
Page: 44-54
PDF size: 405.65 Kb.

ABSTRACT

Background: Dengue in Mexico aff ects all its geography. The 4 viruses in co-circulation provoke different clinical presentations, even severe cases. In 2009, a dengue epidemic occurred in the metropolitan area of Guadalajara, Jalisco, Mexico, followed by the influenza pandemic due to H1N1pdm09. In the Civil Hospital of Guadalajara, “Fray Antonio Alcalde”, a scoring system for dengue was implemented, this system, along with a system for influenza, helped to differentiate both pathologies. Method: Two scoring systems were applied to adults aged 18 or older who presented themselves with a nonspecific acute febrile syndrome (NAFS) during April-December 2009. 5653 patients were evaluated with NAFS, of these 3593 had a positive score for influenza and 2060 for dengue. The blood specimens were processed for NS1 antigens and IgG and IgM serologies for dengue viruses 1-4, as well as nasopharyngeal secretion samples for RTPCR for Influenza. Results: Patients with dengue were older than those with influenza, 33.75 years vs. 30.73 years (p = 0.027). The duration with fever before going to medical attention was 3.31 days in patients with dengue. 2.75 days in patients with influenza (‹0.011). Fever, headache and myalgias were higher in patients with dengue than in patients with influenza, 99.4% vs. 85.2%, 98.1% vs. 88.4%, 98.1% vs. 81.9%, respectively. There was more thrombocytopenia, leukopenia and lymphopenia ocurring in dengue than in patients with influenza. Conclusions: The scoring system in NAFS, for influenza and dengue is of great clinical utility and helps in the timely diagnosis and early treatment.

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